Nitric Oxide Synthase 3D structures: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
32,849 edits
New page: == 3D Structures of Nitric Oxide Synthase == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Endothelial NOS **[[...
 
Michal Harel (talk | contribs)
32,849 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 4: Line 4:
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Endothelial NOS
* Endothelial NOS oxygenase domain (OD) 66-492


**[[3eah]] – h-eNOS OD - human<br />
**[[3nos]], [[4d1o]] – h-eNOS OD+ Arg - human
**[[3nos]], [[4d1o]] – h-eNOS OD+arginine<br />
**[[1m9j]] – h-eNOS OD+chlorzoxazone
**[[1m9j]] – h-eNOS OD+chlorzoxazone<br />
**[[1m9k]], [[1m9r]], [[3eah]], [[4d1p]], [[6av6]], [[6av7]], [[6cie]], [[6cif]], [[6nh1]], [[6nh2]], [[6nh3]], [[6nh4]], [[6nh5]], [[6nh6]], [[6nh7]], [[6nh8]], [[6nhf]] – h-eNOS OD+ inhibitor
**[[1m9k]], [[1m9r]], [[4d1p]], [[6av7]], [[6av6]], [[6nhf]], [[6nh8]], [[6nh7]], [[6nh6]], [[6nh5]], [[6nh4]], [[6nh3]], [[6nh2]], [[6nh1]], [[6cif]], [[6cie]] – h-eNOS OD+ inhibitor<br />
**[[1nsi]] - h-eNOS OD+ Zn
**[[1nsi]] - h-eNOS OD+ Zn<br />
**[[3dqs]], [[3dqt]], [[3jww]], [[3jwx]], [[3jwy]], [[3jwz]], [[3nld]], [[3nle]], [[3nlf]], [[3nlg]], [[3pnh]], [[4luw]] – b-eNOS OD+ pyridine derivative – bovine
**[[3nld]], [[3nle]], [[3nlf]], [[3nlg]], [[3jww]], [[3jwx]], [[3jwy]], [[3jwz]], [[3dqs]], [[3dqt]], [[3pnh]], [[4luw]] – b-eNOS OD+pyrrolidinomethyl pyridine derivative – bovine<br />
**[[1dm6]] – b-eNOS OD+guanidine derivative
**[[1dm6]] – b-eNOS OD+guanidine derivative<br />
**[[3nlh]], [[3rqo]], [[3rqp]] – b-eNOS OD (mutant)+ pyridine derivative
**[[3nlh]], [[3rqo]], [[3rqp]] – b-eNOS OD (mutant)+pyrrolidinomethyl aminopyridine derivative<br />
**[[1p6n]], [[1rs8]], [[1rs9]] – b-eNOS OD +dipeptide inhibitor
**[[1rs8]], [[1rs9]], [[1p6n]] – b-eNOS OD +dipeptide inhibitor<br />
**[[1nse]] – b-eNOS OD
**[[1nse]] – b-eNOS OD<br />
**[[1dm7]], [[1fol]], [[1foo]], [[1fop]], [[2nse]], [[3nse]], [[4nse]], [[5nse]],  – b-eNOS OD+ Arg derivative
**[[1p6n]] – b-eNOS OD +dipeptide inhibitor<br />
**[[7nse]] – b-eNOS OD+ADMA
**[[5nse]], [[1fol]], [[1foo]], [[1fop]], [[1dm7]], [[2nse]], [[3nse]], [[4nse]] – b-eNOS OD+arginine derivative<br />
**[[1d1v]], [[1d1x]], [[1d1y]], [[1ed4]], [[9nse]] – b-eNOS OD+urea derivative
**[[6nse]] – b-eNOS OD+canavanine<br />
**[[1dmj]], [[1dmk]] – b-eNOS OD+pterin derivative
**[[7nse]] – b-eNOS OD+ADMA<br />
**[[1dmi]], [[1foi]], [[1i83]], [[3e7s]], [[3n5p]], [[3n5q]], [[3n5r]], [[3n5s]], [[3n5t]], [[3n5v]], [[3n5w]], [[3n5x]], [[3n5y]], [[3n5z]], [[3n60]], [[3n61]], [[3n62]], [[3n63]], [[3n64]], [[3n65]], [[3n66]], [[3n67]], [[3n68]], [[3n69]], [[3n6a]], [[3n6b]], [[3n6c]], [[3n6d]], [[3n6e]], [[3n6f]], [[3n6g]], [[3nlt]], [[3nlu]], [[4cty]], [[4ctz]], [[4cu0]], [[4cu1]], [[4cul]], [[4cum]], [[4cun]], [[4cvg]], [[4cwv]], [[4cww]], [[4cwx]], [[4cwy]], [[4d33]], [[4d34]], [[4d35]], [[4d36]], [[4d37]], [[4d38]], [[4d39]], [[4d3a]], [[4upq]], [[4upr]], [[4ups]], [[4upt]], [[5adj]], [[5adk]], [[5adl]], [[5adm]], [[5adn]], [[5fj2]], [[5fj3]], [[5fvy]], [[5fvz]], [[5vv6]], [[5vv7]], [[5vv8]], [[5vv9]], [[5vva]], [[5vvb]], [[5vvc]], [[5vvd]], [[5vvg]], [[5vvn]], [[5uo8]], [[5uo9]], [[5uoa]], [[5uob]], [[5uoc]], [[5uod]] – b-eNOS OD+inhibitor
**[[1i83]], [[1d1v]], [[1d1x]], [[1d1y]], [[1ed4]], [[9nse]] – b-eNOS OD+urea derivative<br />
**[[1dmj]], [[1dmk]] – b-eNOS OD+pterin derivative<br />
**[[1foi]], [[1dmi]], [[1i83]], [[3n5p]], [[3n5q]], [[3n5r]], [[3n5s]], [[3n5t]], [[3n5v]], [[3n5w]], [[3n5x]], [[3n5y]], [[3n5z]], [[3n60]], [[3n61]], [[3n62]], [[3n63]], [[3n64]], [[3n65]], [[3n66]], [[3n67]], [[3n68]], [[3n69]], [[3n6a]], [[3n6b]], [[3n6c]], [[3n6d]], [[3n6e]], [[3n6f]], [[3n6g]], [[3nlt]], [[3nlu]], [[3e7s]], [[5vv6]], [[5vv7]], [[5vv8]], [[5vv9]], [[4upq]], [[4upr]], [[4ups]], [[4upt]], [[5vva]], [[5vvb]], [[5vvc]], [[5vvd]], [[5vvg]], [[5vvn]], [[5uo8]], [[5uo9]], [[5uoa]], [[5uob]], [[5uoc]], [[5uod]], [[5fvy]], [[5fvz]], [[5fj2]], [[5fj3]], [[5adj]], [[5adk]], [[5adl]], [[5adm]], [[5adn]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]], [[4d33]], [[4d34]], [[4d35]], [[4d36]], [[4d37]], [[4d38]], [[4d39]], [[4d3a]], [[4cul]], [[4cum]], [[4cun]], [[4cvg]], [[4cwv]], [[4cww]], [[4cwx]], [[4cwy]], [[4cty]], [[4ctz]], [[4cu0]], [[4cu1]] – b-eNOS OD+inhibitor<br />
**[[4cwz]], [[4cx0]], [[4cx1]], [[4cx2]]  – b-eNOS OD (mutant) +inhibitor<br />
**[[4cwz]], [[4cx0]], [[4cx1]], [[4cx2]]  – b-eNOS OD (mutant) +inhibitor<br />
**[[1d0c]], [[8nse]], [[1foj]], [[1ed5]], [[1d0o]], [[1d1w]] – b-eNOS OD+indazole derivative<br />
**[[1d0c]], [[1d0o]], [[1d1w]], [[1ed5]], [[1foj]], [[8nse]] – b-eNOS OD+indazole derivative
**[[1dm8]] – b-eNOS OD+triazole derivative<br />
**[[1dm8]] – b-eNOS OD+triazole derivative
**[[1ed6]] – b-eNOS OD+NO<br />
**[[1ed6]] – b-eNOS OD+NO
**[[1q2o]] – b-eNOS OD (mutant)+dipeptide inhibitor<br />
**[[1p6l]], [[1p6m]] – r-eNOS OD +dipeptide inhibitor - rat<br />
**[[3nli]] - r-eNOS OD (mutant)+pyrrolidinomethyl aminopyridine derivative<br />
**[[4jsk]], [[4jsl]], [[4jsm]], [[4imx]], [[4k5h]], [[4k5i]], [[4k5j]], [[4k5k]], [[4c3a]] – r-eNOS OD+ pyridine derivative<br />
**[[4kcp]], [[4kcq]], [[4kcr]], [[4kcs]] - r-eNOS OD heme domain +thiophene carboximidamide derivative<br />


*Neuronal NOS
* Endothelial NOS heme domain


**[[4uh5]], [[6av5]], [[6av4]], [[6av3]] - h-nNOS heme domain +inhibitor<br />
**[[6pou]], [[6pov]], [[6pow]], [[6pox]], [[6poy]], [[6poz]], [[6pp0]], [[6pp1]], [[6pp2]], [[6pp3]], [[6pp4]], [[7m56]], [[7tsg]], [[7tsh]], [[7tsi]], [[7tsk]], [[7tsl]], [[7tsm]], [[7tsn]], [[7tso]], [[7tsp]], [[7uao]], [[8fge]], [[8fgn]], [[8fgo]], [[8fgp]], [[8fgq]], [[8fgr]], [[8fgs]], [[8fgt]], [[8fgu]], [[8ufr]], [[8uft]], [[8ufu]], [[9c1z]], [[9cw5]], [[9cw6]], [[9cw7]], [[9cw9]], [[9cwj]], [[9cwk]], [[9mwo]], [[9mws]], [[9mwt]], [[9mwu]], [[9mwv]], [[9mww]], [[9mz1]], [[9mz2]], [[9mz3]], [[9mz4]], [[9q4y]], [[9q51]], [[9q52]], [[9q54]], [[9q55]], [[9q58]] – h-eNOS heme domain + inhibitor<br />
**[[4uh6]], [[4uch]], [[6av2]], [[6av1]], [[6av0]], [[6auz]], [[6auy]], [[5vv4]], [[5vv2]], [[5vv1]], [[5vuz]], [[5vuy]], [[5vux]], [[5vuw]], [[5vuv]], [[6nhb]], [[6nhc]], [[6cid]], [[6ng8]], [[6ngi]], [[6ngh]], [[6ngf]], [[6nge]], [[6ngd]], [[6ngc]], [[6ngb]], [[6nga]], [[6ng7]], [[6ng6]], [[6ng5]], [[6ng4]], [[6ng2]], [[6ng1]], [[6cic]] - h-nNOS heme domain + inhibitor<br />
**[[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]] – h-eNOS heme domain (mutant) + inhibitor<br />
**[[4d1n]] - h-nNOS heme domain (mutant) + arginine<br />
**[[1q2o]] – b-eNOS OD (mutant)+dipeptide inhibitor
**[[2hx2]] – b-nNOS OD+nitroguanidine derivative<br />
**[[6nse]] - b-eNOS heme domain + canavanine<br />
**[[3nlv]], [[3nlw]], [[3nlx]], [[3nly]], [[3nlz]], [[3nm0]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]] - b-nNOS OD + inhibitor<br />
**[[1p6l]], [[1p6m]] – r-eNOS OD +dipeptide inhibitor – rat
**[[3nli]], [[3nlj]], [[3nlk]], [[3nln]], [[3nlo]], [[3nlp]], [[3nlq]], [[3nlr]], [[3jws]], [[3jwt]], [[3jwu]], [[3jwv]], [[3jx0]], [[3jx1]], [[3jx2]], [[3jx3]], [[3jx4]], [[3jx5]], [[3jx6]], [[3pne]], [[3pnf]], [[3png]], [[3svp]], [[3svq]] - r-nNOS OD (mutant)+ pyridine derivative – rat<br />
**[[4c3a]], [[4imx]], [[4jsk]], [[4jsl]], [[4jsm]], [[4k5h]], [[4k5i]], [[4k5j]], [[4k5k]] – r-eNOS OD+ pyridine derivative<br />
**[[3nlm]], [[3nny]], [[3nnz]], [[3n2r]], [[3b3o]], [[3b3p]], [[3b3m]], [[3b3n]], [[3rqj]], [[3rqk]], [[3rql]], [[3rqm]], [[3rqn]], [[3tyl]], [[3tym]], [[3tyn]], [[3tyo]], [[4ims]], [[4imt]], [[4imu]], [[4imw]], [[4jse]], [[4jsf]], [[4jsg]], [[4jsh]], [[4jsi]], [[4jsj]], [[4k5d]], [[4k5e]], [[4k5f]], [[4k5g]], [[4lux]] - r-nNOS OD+ pyridine derivative<br />
**[[4kcp]], [[4kcq]], [[4kcr]], [[4kcs]] - r-eNOS OD +thiophene carboximidamide derivative<br />
**[[4uh0]], [[4uh1]], [[4uh2]], [[4uh3]], [[4uh4]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]], [[6ngj]], [[6ngk]], [[6ngl]], [[6ngm]], [[6ngn]], [[6ngp]], [[6ngq]], [[6ngr]], [[6ngs]], [[6ngt]], [[6ngu]], [[6ngv]], [[6ngw]], [[6ngx]], [[6ngy]], [[6ngz]], [[6nh0]] – r-eNOS heme domain + inhibitor<br />
 
*Neuronal NOS;  heme domain 297-718
 
**[[4uh5]], [[6av3]], [[6av4]], [[6av5]], [[7ts8]], [[7tsf]], [[9cvn]], [[9q4z]] - h-nNOS heme domain +inhibitor<br />
**[[4uch]], [[4uh6]], [[5vuv]], [[5vuw]], [[5vux]], [[5vuy]], [[5vuz]], [[5vv1]], [[5vv2]], [[5vv4]], [[6auz]], [[6auy]], [[6av0]], [[6av1]], [[6av2]], [[6cic]], [[6cid]], [[6ng1]], [[6ng2]], [[6ng4]], [[6ng5]], [[6ng6]], [[6ng7]], [[6ng8]], [[6nga]], [[6ngb]], [[6ngc]], [[6ngd]], [[6nge]], [[6ngf]], [[6ngh]], [[6ngi]], [[6nhb]], [[6nhc]], [[6pna]], [[6pnb]], [[6pnc]], [[6pnd]], [[6pne]], [[6pnf]], [[6png]], [[6pnh]], [[6po5]], [[6po7]], [[6po8]], [[6po9]], [[6poa]], [[6pob]], [[6poc]], [[6pot]], [[7ts1]], [[7ts2]], [[7ts3]], [[7ts4]], [[7ts5]], [[7ts6]], [[7ts6]], [[7uam]], [[7us7]], [[7us8]], [[8fgf]], [[8fgg]], [[8fgh]], [[8fgi]], [[8fgk]], [[8fgl]], [[8fgm]], [[9cvo]], [[9cvp]], [[9cvq]], [[9cvs]], [[9cvu]], [[9cvv]], [[9cvx]], [[9cvy]], [[9cvz]], [[9cw0]], [[9cw1]], [[9cw3]], [[9myw]], [[9mwb]], [[9q4i]], [[9q4j]], [[9q4n]], [[9q4o]], [[9q4w]] - h-nNOS heme domain (mutant) +inhibitor<br />
**[[4d1n]] - h-nNOS heme domain (mutant) + Arg<br />
**[[4cam]], [[4can]], [[4cao]], [[4cap]], [[4caq]], [[4car]], [[4cdt]], [[4cft]] – r-nNOS heme domain + quinoline derivative<br />
**[[4kch]], [[4kci]], [[4kcj]], [[4kck]], [[4kcl]], [[4kcm]], [[4kcn]], [[4kco]] - r-nNOS heme domain + carboximidamide derivative<br />
**[[9mwa]], [[9mwc]], [[9mwe]], [[9mwf]], [[9mwg]], [[9mwh]], [[9mwk]], [[9mwm]] - r-nNOS heme domain (mutant) + carboximidamide derivative<br />
**[[6nhd]], [[6nhe]], [[6pmv]], [[6pmw]], [[6pmx]], [[6pmy]], [[6pmz]], [[6pn0]], [[6pn1]], [[6pn2]], [[6pn3]], [[6pn4]], [[6pn5]], [[6pn6]], [[6pn7]], [[6pn8]], [[6pn9]], [[7s3x]], [[7s3y]], [[7s3z]], [[7s40]], [[8fgb]], [[8fgc]] - r-nNOS heme domain +inhibitor<br />
**[[7ts9]], [[7tsa]], [[7tsb]], [[7tsc]], [[7tsd]], [[7tse]], [[7uan]], [[9cvi]], [[9cvl]], [[9myy]], [[9q4p]], [[9q4r]], [[9q4t]] - r-nNOS heme domain (mutant) + inhibitor<br />
 
*Neuronal NOS;  oxygenase domain (OD) 297-718
 
**[[2hx2]] – b-nNOS OD+nitroguanidine derivative
**[[3nlv]], [[3nlw]], [[3nlx]], [[3nly]], [[3nlz]], [[3nm0]] - b-nNOS OD + inhibitor
**[[3nlj]], [[3nlk]], [[3nln]], [[3nlo]], [[3nlp]], [[3nlq]], [[3nlr]], [[3jws]], [[3jwt]], [[3jwu]], [[3jwv]], [[3jx0]], [[3jx1]], [[3jx2]], [[3jx3]], [[3jx4]], [[3jx5]], [[3jx6]], [[3pne]], [[3pnf]], [[3png]], [[3svp]], [[3svq]] – r-nNOS OD (mutant)+pyridine derivative  
**[[3b3m]], [[3b3n]], [[3b3o]], [[3b3p]], [[3n2r]], [[3nlm]], [[3nny]], [[3nnz]], [[3rqj]], [[3rqk]], [[3rql]], [[3rqm]], [[3rqn]], [[3tyl]], [[3tym]], [[3tyn]], [[3tyo]], [[4ims]], [[4imt]], [[4imu]], [[4imw]], [[4jse]], [[4jsf]], [[4jsg]], [[4jsh]], [[4jsi]], [[4jsj]], [[4k5d]], [[4k5e]], [[4k5f]], [[4k5g]], [[4lux]] – r-nNOS OD+ pyridine derivative
**[[1k2r]], [[1k2s]], [[1lzx]], [[1om4]], [[1qw6]], [[1zvl]], [[2hx4]], [[4fvw]], [[4fvx]], [[4fvy]], [[4fvz]], [[4fw0]]  – r-nNOS OD+ Arg derivative
**[[4gqe]]  – r-nNOS OD + norvaline derivative<br />
**[[4gqe]]  – r-nNOS OD + norvaline derivative<br />
**[[1om4]], [[1k2r]], [[1k2s]], [[1lzx]], [[2hx4]], [[1zvl]], [[1qw6]], [[4fvw]], [[4fvx]], [[4fvy]], [[4fvz]], [[4fw0]] - r-nNOS OD+arginine derivative<br />
**[[1k2t]], [[1k2u]] – r-nNOS OD+thiourea derivative
**[[4cam]], [[4can]], [[4cao]], [[4cap]], [[4caq]], [[4car]], [[4cdt]], [[4cft]]  – r-nNOS OD heme domain + quinoline derivative<br />
**[[1om5]] – r-nNOS OD+indazole derivative
**[[1k2t]], [[1k2u]] – r-nNOS OD+thiourea derivative<br />
**[[1lzz]], [[1m00]], [[2hx3]] – r-nNOS OD+guanidine derivative
**[[1om5]] – r-nNOS OD+indazole derivative<br />
**[[1zvi]], [[3fc5]] – r-nNOS OD
**[[1lzz]], [[1m00]], [[2hx3]]– r-nNOS OD+guanidine derivative<br />
**[[1mmv]], [[1mmw]], [[1qwc]], [[3dqr]], [[3q99]], [[3q9a]], [[3ufo]], [[3ufp]], [[3ufq]], [[3ufr]], [[3ufs]], [[3uft]], [[3ufu]], [[3ufv]], [[3ufw]], [[4c39]], [[4ctp]], [[4ctq]], [[4ctr]], [[4ctt]], [[4ctu]], [[4ctv]], [[4ctw]], [[4ctx]], [[4d1z]], [[4d2y]], [[4d2z]], [[4d30]], [[4d31]], [[4d32]], [[4d33]], [[4d34]], [[4d35]], [[4d3b]], [[4d7o]], [[4eux]], [[4ugz]], [[4upm]], [[4upn]], [[4upo]], [[4upp]], [[4v3v]], [[4v3w]], [[4v3x]], [[4v3y]], [[4v3z]], [[5ad4]], [[5ad5]], [[5ad6]], [[5ad7]], [[5ad8]], [[5ad9]], [[5ada]], [[5adb]], [[5adc]], [[5vui]], [[5fvo]], [[5fvp]], [[5fvq]], [[5fvr]], [[5fvs]], [[5fvt]], [[5fw0]], [[5unr]], [[5unt]], [[5unu]], [[5unv]], [[5unw]], [[5unx]], [[5uny]], [[5unz]], [[5uo0]], [[5vuj]], [[5vuk]], [[5vul]], [[5vum]], [[5vun]], [[5vuo]], [[5vup]], [[5vuq]], [[5vur]], [[5vus]], [[5vut]], [[5vuu]], [[6auq]], [[6aur]], [[6aut]], [[6auu]], [[6auv]], [[6auw]], [[6aux]], [[6ngj]], [[6ngk]], [[6ngl]], [[6ngm]], [[6ngn]], [[6ngp]], [[6ngq]], [[6ngr]], [[6ngs]], [[6ngt]], [[6ngu]], [[6ngv]], [[6ngw]], [[6ngx]], [[6ngy]], [[6ngz]], [[6nh0]], [[6nhd]], [[6nhe]], [[7tsf]] – r-nNOS OD+inhibitor
**[[4kch]], [[4kci]], [[4kcj]], [[4kck]], [[4kcl]], [[4kcm]], [[4kcn]], [[4kco]] - r-nNOS OD heme domain +thiophene carboximidamide derivative<br />
**[[4cx3]], [[4cx4]], [[4cx5]], [[4cx6]], [[4v3u]], [[5add]], [[5ade]], [[5adf]], [[5adg]], [[5adi]], [[5fvu]], [[5fvv]], [[5fvx]], [[5fvw]], [[5g0n]], [[5g0o]], [[5g0p]], [[5uns]], [[5uo1]], [[5uo2]], [[5uo3]], [[5uo4]], [[5uo5]], [[5uo6]], [[5uo7]], [[5vv0]], [[5vv3]], [[5vv5]], [[6aus]] – r-nNOS OD (mutant) +inhibitor<br />
**[[3fc5]], [[1zvi]] – r-nNOS OD<br />
**[[3jt3]], [[3jt4]], [[3jt5]], [[3jt6]], [[3jt7]], [[3jt8]], [[3jt9]], [[3jta]] – r-nNOS OD+ornithine derivative
**[[1qau]] - r-nNOS OD PDZ domain<br />
**[[3hsn]] – r-nNOS OD+NHA+CO
**[[1qav]], [[4hop]] - r-nNOS OD PDZ domain + α-1 syntrophin<br />
**[[3hso]], [[3hsp]] -  r-nNOS OD+NHA+NO
**[[1qwc]], [[3q99]], [[3q9a]], [[1mmv]], [[1mmw]], [[3dqr]], [[3ufo]], [[3ufp]], [[3ufq]], [[3ufr]], [[3ufs]], [[3uft]], [[3ufu]], [[3ufv]], [[3ufw]], [[4eux]], [[5vui]], [[4upm]], [[4upn]], [[4upo]], [[4upp]], [[5vuk]], [[5vul]], [[5vum]], [[5vun]], [[5vuo]], [[5vup]], [[5vuq]], [[5vur]], [[5vus]], [[5vut]], [[5vuu]], [[5unr]], [[5unt]], [[5unu]], [[5unv]], [[5unw]], [[5unx]], [[5uny]], [[5unz]], [[5uo0]], [[5fw0]], [[5fvo]], [[5fvp]], [[5fvq]], [[5fvr]], [[5fvs]], [[5fvt]], [[5agk]], [[5agl]], [[5agm]], [[5agn]], [[5ago]], [[5agp]], [[4v3v]], [[4v3w]], [[4v3x]], [[4v3y]], [[4v3z]], [[5ad4]], [[5ad5]], [[5ad6]], [[5ad7]], [[5ad8]], [[5ad9]], [[5ada]], [[5adb]], [[5adc]], [[4ugz]], [[4d33]], [[4d34]], [[4d35]], [[4d2y]], [[4d1z]], [[4d30]], [[4d31]], [[4uh4]], [[4d7o]], [[4d3b]], [[4d32]], [[4ctp]], [[4ctq]], [[4ctr]], [[4ctt]], [[4ctu]], [[4ctv]], [[4c39]], [[6aux]], [[6auw]], [[6auv]], [[6auu]], [[6aut]], [[6aur]], [[6auq]], [[5vuj]], [[4uh3]], [[4uh2]], [[4uh1]], [[4uh0]], [[4d2z]], [[4ctx]], [[4ctw]], [[6nhe]], [[6nhd]], [[6nh0]], [[6ngz]], [[6ngy]], [[6ngx]], [[6ngw]], [[6ngv]], [[6ngu]], [[6ngt]], [[6ngs]], [[6ngr]], [[6ngq]], [[6ngp]], [[6ngn]], [[6ngm]], [[6ngl]], [[6ngk]], [[6ngj]] – r-nNOS OD+inhibitor<br />
**[[2g6h]], [[2g6i]], [[2g6j]] – r-nNOS OD+pterin derivative
**[[5vv0]], [[5vv3]], [[5vv5]], [[5uns]], [[5uo1]], [[5uo2]], [[5uo3]], [[5uo4]], [[5uo5]], [[5uo6]], [[5uo7]], [[5g0n]], [[5g0p]], [[5fvu]], [[5fvv]], [[5fvx]], [[5fvw]], [[5fvx]], [[4v3u]], [[5add]], [[5ade]], [[5adf]], [[5adg]], [[5adi]], [[4cx3]], [[4cx4]], [[4cx5]], [[4cx6]], [[6aus]], [[5g0o]] – r-nNOS OD (mutant) +inhibitor<br />
**[[2g6k]], [[2g6l]] – r-nNOS OD+pterin derivative+NO
**[[3jt3]], [[3jt4]], [[3jt5]], [[3jt6]], [[3jt7]], [[3jt8]], [[3jt9]], [[3jta]] – r-nNOS OD+ornithine derivative<br />
**[[2g6m]], [[2g6n]], [[2g6o]] – r-nNOS OD+pterin derivative+CO
**[[3hsn]] – r-nNOS OD+NHA+CO<br />
**[[1p6k]], [[1zzq]], [[1zzr]], [[1zzs]], [[1zzt]], [[1zzu]] – r-nNOS OD (mutant)+dipeptide inhibitor
**[[3hso]], [[3hsp]] -  r-nNOS OD+NHA+NO<br />
**[[1p6h]], [[1p6i]], [[1p6j]], [[1rs6]], [[1rs7]] – r-nNOS OD +dipeptide inhibitor
**[[2g6h]], [[2g6i]], [[2g6j]] – r-nNOS OD+pterin derivative<br />
**[[1vag]] – m-nNOS OD+inhibitor – mouse
**[[2g6k]], [[2g6l]] – r-nNOS OD+pterin derivative+NO<br />
**[[2g6m]], [[2g6n]], [[2g6o]] – r-nNOS OD+pterin derivative+CO<br />
**[[1zzq]], [[1zzr]], [[1zzs]], [[1zzt]], [[1zzu]], [[1p6k]] – r-nNOS OD (mutant)+dipeptide inhibitor<br />
**[[1rs6]], [[1rs7]], [[1p6h]], [[1p6i]], [[1p6j]] – r-nNOS OD +dipeptide inhibitor<br />
**[[1b8q]] – r-nNOS PDZ domain + heptapeptide<br />
**[[1f20]] - r-nNOS FAD/NADP domain<br />
**[[1vag]] – m-nNOS OD+inhibitor - mouse<br />


*Inducible NOS
*Neuronal NOS;  other domains
   
 
**[[3hr4]] – h-iNOS residues 503-715+calmodulin <br />
**[[8t1j]] - r-nNOS  + Arg – Cryo EM
**[[3e7g]] – h-iNOS residues 82-505+inhibitor<br />
**[[1qau]] - r-nNOS PDZ domain
**[[3ej8]] – h-iNOS OD+imidazole<br />
**[[1qav]], [[4hop]] - r-nNOS PDZ domain + α-1 syntrophin
**[[4nos]], [[4cx7]] – h-iNOS OD+inhibitor<br />
**[[1b8q]] – r-nNOS PDZ domain + heptapeptide
**[[1nsi]] – h-iNOS OD+arginine<br />
**[[1f20]] - r-nNOS FAD/NADP domain
**[[2nsi]] – h-iNOS OD+thiourea derivative<br />
**[[1tll]] – r-nNOS resdues 742-1429<br />
**[[3nqs]], [[3e65]], [[3eai]], [[3ebd]], [[3ebf]], [[1r35]], [[2nod]]  – m-iNOS OD + pterin derivative<br />
*Inducible NOS
**[[1jwj]], [[1jwk]] – m-iNOS OD (mutant)+ pterin derivative<br />
**[[3hr4]] – h-iNOS residues 503-715+calmodulin
**[[3e7g]], [[3ej8]], [[4cx7]], [[4nos]] – h-iNOS OD+inhibitor
**[[4nsi]] – h-iNOS OD+ Arg
**[[2nsi]] – h-iNOS OD+thiourea derivative
**[[6key]] - h-iNOS OD + SOCS box protein<br />
**[[1r35]], [[2nod]], [[3e65]], [[3eai]], [[3ebd]], [[3ebf]], [[3nsq]]  – m-iNOS OD + pterin derivative  
**[[1jwj]], [[1jwk]] – m-iNOS OD (mutant)+ pterin derivative
**[[4ux6]] – m-iNOS OD + pterin derivative + inhibitor<br />
**[[4ux6]] – m-iNOS OD + pterin derivative + inhibitor<br />
**[[2bhj]] – m-iNOS OD+coumarin<br />
**[[2bhj]] – m-iNOS OD+coumarin
**[[3nod]] – m-iNOS OD+product analog<br />
**[[3nod]] – m-iNOS OD+product analog
**[[1noc]] – m-iNOS OD+chloramphenicol acetyltransferase<br />
**[[1noc]] – m-iNOS OD+chloramphenicol acetyltransferase
**[[3e67]] – m-iNOS OD+4-MAP<br />
**[[3e67]] – m-iNOS OD+4-MAP
**[[3e68]], [[3e6l]], [[3e6n]], [[3e6o]], [[3e6t]], [[3e7i]], [[3e7m]], [[3e7t]], [[1vaf]], [[1qw5]], [[1dd7]], [[2y37]] – m-iNOS OD+inhibitor <br />
**[[1dd7]], [[1qw5]], [[1vaf]], [[2y37]], [[3e68]], [[3e6l]], [[3e6n]], [[3e6o]], [[3e6t]], [[3e7i]], [[3e7m]], [[3e7t]] – m-iNOS OD+inhibitor  
**[[2orq]], [[2orr]], [[2ors]], [[2ort]], [[2oro]], [[2orp]], [[1nos]], [[3nw2]] – m-iNOS OD+imidazole derivative<br />
**[[1nos]], [[2oro]], [[2orp]], [[2orq]], [[2orr]], [[2ors]], [[2ort]], [[3nw2]] – m-iNOS OD+imidazole derivative
**[[1df1]] - m-iNOS OD+ urea derivative<br />
**[[1df1]] - m-iNOS OD+ urea derivative
**[[3dwj]] – m-iNOS OD (mutant)<br />
**[[3dwj]] – m-iNOS OD (mutant)
**[[1qom]], [[4js9]] - m-iNOS OD<br />
**[[1qom]], [[4js9]] - m-iNOS OD
**[[1qw4]], [[1dwv]], [[1dww]], [[1dwx]], [[1nod]] – m-iNOS OD+arginine derivative<br />
**[[1dwv]], [[1dww]], [[1dwx]], [[1nod]], [[1qw4]] – m-iNOS OD + Arg derivative
**[[2nos]] – m-iNOS OD+guanidine derivative<br />
**[[2nos]] – m-iNOS OD+guanidine derivative
**[[1n2n]] – m-iNOS OD+CN<br />
**[[1n2n]] – m-iNOS OD+CN
**[[1m9t]] – m-iNOS OD+indazole derivative<br />
**[[1m9t]] – m-iNOS OD+indazole derivative
**[[1m8d]] – m-iNOS OD+chlorzoxazone<br />
**[[1m8d]] – m-iNOS OD+chlorzoxazone
**[[1m8e]], [[1m8h]], [[1m8i]], [[1m9m]], [[1m9q]] – m-iNOS OD+ indazole derivative<br />
**[[1m8e]], [[1m8h]], [[1m8i]], [[1m9m]], [[1m9q]] – m-iNOS OD+ indazole derivative
**[[1jwj]] – m-iNOS OD + inhibitor<br />
**[[1jwk]] - m-iNOS OD (mutant) + inhibitor<br />
**[[3gof]] - c-iNOS OD + calmodulin – chicken<br />
**[[3gof]] - c-iNOS OD + calmodulin – chicken<br />


*Prokaryote NOS
*Prokaryote NOS


**[[2amo]] – BsNOS – ''Bacillus subtilis''<br />
**[[2amo]] – BsNOS – ''Bacillus subtilis''
**[[2an0]], [[2an2]] – BsNOS (mutant)<br />
**[[2an0]], [[2an2]] – BsNOS (mutant)
**[[2fbz]], [[2fc2]], [[2fc1]] – BsNOS+NO<br />
**[[2fbz]], [[2fc1]], [[2fc2]] – BsNOS+NO
**[[1m7v]], [[1m7z]] – BsNOS+THF+arginine<br />
**[[1m7v]], [[1m7z]] – BsNOS+THF+ Arg
**[[5g67]], [[5g6q]], [[5g6p]], [[5g6o]], [[5g6n]], [[5g6m]], [[5g6l]], [[5g6k]], [[5g6j]], [[5g6i]], [[5g6h]], [[5g6g]], [[5g6f]], [[5g6e]], [[5g6d]], [[5g6c]], [[5g6b]], [[5g6a]], [[5g69]], [[5g68]], [[5g66]], [[5g65]], [[4ugl]], [[4uqs]], [[4uqr]], [[4ugy]], [[4ugx]], [[4ugw]], [[4ugv]], [[4ugu]], [[4ugt]], [[4ugs]], [[4ugr]], [[4ugq]], [[4ugp]], [[4ugo]], [[4ugn]], [[4ugm]], [[4ugk]], [[4ugj]], [[4ugi]], [[4ugh]], [[4ugg]], [[4ugf]], [[4uge]], [[4ugd]], [[4ugc]], [[4ugb]], [[4uga]], [[4ug9]], [[4ug8]], [[4ug7]], [[4ug6]], [[4ug5]], [[4lwb]], [[4lwa]], [[4d7j]], [[4d7i]], [[4d7h]], [[4d3v]], [[4d3u]], [[4d3t]], [[4d3o]], [[4d3n]], [[4d3m]], [[4d3k]], [[4d3j]], [[4d3i]] – BsNOS (mutant) + inhibitor<br />
**[[6xcx]], [[6xk3]], [[6xk4]], [[6xk5]], [[6xk6]], [[6xk7]], [[6xk8]], [[6xmc]] – BsNOS + inhibitor<br />
**[[2flq]] – NOS+arginine – ''Geobacillus stearothermophilus''<br />
**[[4d3v]], [[4d3u]], [[4d3t]], [[4d3o]], [[4d3n]], [[4d3m]], [[4d3k]], [[4d3j]], [[4d3i]], [[4d7h]], [[4d7i]], [[4d7j]], [[4lwa]], [[4lwb]], [[4ug5]], [[4ug6]], [[4ug7]], [[4ug8]], [[4ug9]], [[4uga]], [[4ugb]], [[4ugc]], [[4ugd]], [[4uge]], [[4ugf]], [[4ugg]], [[4ugh]], [[4ugi]], [[4ugj]], [[4ugk]], [[4ugl]], [[4ugm]], [[4ugn]], [[4ugo]], [[4ugp]], [[4ugq]], [[4ugr]], [[4ugs]], [[4ugt]], [[4ugu]], [[4ugv]], [[4ugw]], [[4ugx]], [[4ugy]], [[4uqr]], [[4uqs]], [[5g67]], [[5g6q]], [[5g6p]], [[5g6o]], [[5g6n]], [[5g6m]], [[5g6l]], [[5g6k]], [[5g6j]], [[5g6i]], [[5g6h]], [[5g6g]], [[5g6f]], [[5g6e]], [[5g6d]], [[5g6c]], [[5g6b]], [[5g6a]], [[5g69]], [[5g68]], [[5g66]], [[5g65]] – BsNOS (mutant) + inhibitor<br />
**[[2flq]] – NOS+ Arg – ''Geobacillus stearothermophilus''
**[[9q0x]] – NOS – ''Synechococcus'' – Cryo EM
 
}}
}}


[[Category:Topic Page]]
[[Category:Topic Page]]
Retrieved from "https://proteopedia.org/Nitric_Oxide_Synthase_3D_structures"