6l95: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6l95 is ~~ON HOLD~~

==transmembrane-domain of Bax==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6l95]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L95 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l95 OCA], [https://pdbe.org/6l95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l95 RCSB], [https://www.ebi.ac.uk/pdbsum/6l95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l95 ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Bo OY]]

[[Category: Fujiao L]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6l95 is ON HOLD
+==transmembrane-domain of Bax==
+<StructureSection load='6l95' size='340' side='right'caption='[[6l95]]' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6l95]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L95 FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l95 OCA], [https://pdbe.org/6l95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l95 RCSB], [https://www.ebi.ac.uk/pdbsum/6l95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l95 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Bo OY]]
+[[Category: Fujiao L]]