6lf7: Difference between revisions
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New page: '''Unreleased structure''' The entry 6lf7 is ON HOLD Authors: Viswanathan, V., Tyagi, T.K., Singh, R.P., Singh, A.K., Singh, A., Bhushan, A., Sinha, M., Kaur, P., Sharma, S., Singh, T.P... |
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==Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.== | |||
<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LF7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.794Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [https://pdbe.org/6lf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [https://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> | |||
==See Also== | |||
*[[Lactoperoxidase|Lactoperoxidase]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Bhushan | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Capra hircus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bhushan A]] | ||
[[Category: Singh | [[Category: Kaur P]] | ||
[[Category: Singh | [[Category: Sharma S]] | ||
[[Category: | [[Category: Singh A]] | ||
[[Category: | [[Category: Singh AK]] | ||
[[Category: | [[Category: Singh RP]] | ||
[[Category: Singh TP]] | |||
[[Category: Sinha M]] | |||
[[Category: Tyagi TK]] | |||
[[Category: Viswanathan V]] | |||
Latest revision as of 13:27, 13 August 2026
Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
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