6v1x: Difference between revisions
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The | ==Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer== | ||
<StructureSection load='6v1x' size='340' side='right'caption='[[6v1x]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6v1x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V1X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QNJ:(3beta,5beta,14beta,17alpha)-cholestan-3-ol'>QNJ</scene>, <scene name='pdbligand=QNP:(2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl+tetradecanoate'>QNP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v1x OCA], [https://pdbe.org/6v1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v1x RCSB], [https://www.ebi.ac.uk/pdbsum/6v1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v1x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KAT1_ARATH KAT1_ARATH] Highly selective inward-rectifying potassium channel. This voltage-gated channel could mediate long-term potassium influx into guard cells leading to stomatal opening. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization. The channel activity is enhanced upon external acidification. Also permeable to ammonium ions. Blocked by tetraethylammonium and barium ions.<ref>PMID:8966547</ref> | |||
==See Also== | |||
*[[Potassium channel 3D structures|Potassium channel 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Clark MD]] | |||
[[Category: Contreras GF]] | |||
[[Category: Perozo E]] | |||
[[Category: Shen R]] | |||
Latest revision as of 14:35, 6 March 2024
Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer
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