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New page: ==Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with cadmium and hydrolyzed moxolactam== <StructureSection load='6uac' size='340' sid...
 
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<StructureSection load='6uac' size='340' side='right'caption='[[6uac]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='6uac' size='340' side='right'caption='[[6uac]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6uac]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strmk Strmk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UAC FirstGlance]. <br>
<table><tr><td colspan='2'>[[6uac]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Stenotrophomonas_maltophilia_K279a Stenotrophomonas maltophilia K279a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UAC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MX1:(2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>MX1</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6u0y|6u0y]], [[6u0z|6u0z]], [[6u10|6u10]], [[6u13|6u13]], [[6u2y|6u2y]], [[6u2z|6u2z]], [[6ua1|6ua1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MX1:(2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBOXYLIC+ACID'>MX1</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Smlt2667 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=522373 STRMK])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uac OCA], [https://pdbe.org/6uac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uac RCSB], [https://www.ebi.ac.uk/pdbsum/6uac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uac ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uac OCA], [http://pdbe.org/6uac PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uac RCSB], [http://www.ebi.ac.uk/pdbsum/6uac PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uac ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B2FTM1_STRMK B2FTM1_STRMK]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Strmk]]
[[Category: Stenotrophomonas maltophilia K279a]]
[[Category: Structural genomic]]
[[Category: Endres M]]
[[Category: Endres, M]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A]]
[[Category: Kim Y]]
[[Category: Kim, Y]]
[[Category: Maltseva N]]
[[Category: Maltseva, N]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Lactam antibiotic]]

Latest revision as of 07:47, 11 October 2023

Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with cadmium and hydrolyzed moxolactam

6uac, resolution 1.60Å

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