2vdd: Difference between revisions

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<StructureSection load='2vdd' size='340' side='right'caption='[[2vdd]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='2vdd' size='340' side='right'caption='[[2vdd]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vdd]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VDD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vdd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VDD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ek9|1ek9]], [[1ttq|1ttq]], [[1tqq|1tqq]], [[2vde|2vde]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdd OCA], [http://pdbe.org/2vdd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vdd RCSB], [http://www.ebi.ac.uk/pdbsum/2vdd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vdd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vdd OCA], [https://pdbe.org/2vdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vdd RCSB], [https://www.ebi.ac.uk/pdbsum/2vdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vdd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TOLC_ECOLI TOLC_ECOLI]] Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells.<ref>PMID:6337123</ref> <ref>PMID:11274125</ref> <ref>PMID:15228545</ref> <ref>PMID:18955484</ref> <ref>PMID:23176499</ref>
[https://www.uniprot.org/uniprot/TOLC_ECOLI TOLC_ECOLI] Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells.<ref>PMID:6337123</ref> <ref>PMID:11274125</ref> <ref>PMID:15228545</ref> <ref>PMID:18955484</ref> <ref>PMID:23176499</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bavro, V N]]
[[Category: Bavro VN]]
[[Category: Fernandez-Recio, J]]
[[Category: Fernandez-Recio J]]
[[Category: Furnham, N]]
[[Category: Furnham N]]
[[Category: Luisi, B]]
[[Category: Luisi B]]
[[Category: Misra, R]]
[[Category: Misra R]]
[[Category: Pei, X Y]]
[[Category: Pei XY]]
[[Category: Perez-Cano, L]]
[[Category: Perez-Cano L]]
[[Category: Pietras, Z]]
[[Category: Pietras Z]]
[[Category: Truer, R]]
[[Category: Truer R]]
[[Category: Alpha helical barrel]]
[[Category: Beta barrel]]
[[Category: Integral membrane protein]]
[[Category: Membrane]]
[[Category: Multidrug efflux pump]]
[[Category: Outer membrane]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Transport protein]]