6p8r: Difference between revisions

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<StructureSection load='6p8r' size='340' side='right'caption='[[6p8r]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='6p8r' size='340' side='right'caption='[[6p8r]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6p8r]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P8R FirstGlance]. <br>
<table><tr><td colspan='2'>[[6p8r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P8R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.141&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6p8o|6p8o]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p8r OCA], [http://pdbe.org/6p8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p8r RCSB], [http://www.ebi.ac.uk/pdbsum/6p8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p8r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p8r OCA], [https://pdbe.org/6p8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p8r RCSB], [https://www.ebi.ac.uk/pdbsum/6p8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p8r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAP7_PSEAI CAP7_PSEAI] CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type III-C(AAA) CBASS system (PubMed:32839535).<ref>PMID:31932165</ref> <ref>PMID:32839535</ref>  The sensor protein for this CBASS system. Binds to a closure peptide (consensus Glu-Val-Met-Glu-Phe-Asn-Pro), which allows it to activate CdnD for second messenger synthesis.<ref>PMID:31932165</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Corbett, K D]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Ye, Q]]
[[Category: Corbett KD]]
[[Category: Cd-ntase]]
[[Category: Ye Q]]
[[Category: Cga]]
[[Category: Horma domain]]
[[Category: Protein binding]]
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