1uec: Difference between revisions

<table><tr><td colspan='2'>[[1uec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UEC FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uec OCA], [https://pdbe.org/1uec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uec RCSB], [https://www.ebi.ac.uk/pdbsum/1uec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uec ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/NCF1_HUMAN NCF1_HUMAN] Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:[https://omim.org/entry/233700 233700]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.<ref>PMID:2011585</ref> <ref>PMID:11133775</ref>  

[https://www.uniprot.org/uniprot/NCF1_HUMAN NCF1_HUMAN] NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).<ref>PMID:19801500</ref>  

[[Category: Homo sapiens]]

[[Category: Fujioka Y]]

[[Category: Inagaki F]]

[[Category: Ogura K]]

[[Category: Sumimoto H]]

[[Category: Suzuki NN]]

[[Category: Yuzawa S]]