6vcc: Difference between revisions

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'''Unreleased structure'''


The entry 6vcc is ON HOLD
==Cryo-EM structure of the Dvl2 DIX filament==
 
<StructureSection load='6vcc' size='340' side='right'caption='[[6vcc]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
Authors: Enos, M., Kan, W., Muennich, S., Skiniotis, G., Weis, W.I.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6vcc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VCC FirstGlance]. <br>
Description: Cryo-EM structure of the Dvl2 DIX filament
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vcc OCA], [https://pdbe.org/6vcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vcc RCSB], [https://www.ebi.ac.uk/pdbsum/6vcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vcc ProSAT]</span></td></tr>
[[Category: Skiniotis, G]]
</table>
[[Category: Kan, W]]
== Function ==
[[Category: Muennich, S]]
[https://www.uniprot.org/uniprot/DVL2_MOUSE DVL2_MOUSE] Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes.<ref>PMID:17199046</ref> <ref>PMID:21189423</ref> <ref>PMID:20947020</ref>
[[Category: Enos, M]]
== References ==
[[Category: Weis, W.I]]
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Chen DH]]
[[Category: Enos M]]
[[Category: Kan W]]
[[Category: Muennich S]]
[[Category: Skiniotis G]]
[[Category: Weis WI]]
Retrieved from "https://proteopedia.org/6vcc"