4keq: Difference between revisions
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<StructureSection load='4keq' size='340' side='right'caption='[[4keq]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='4keq' size='340' side='right'caption='[[4keq]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4keq]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4keq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_japonicum_MAFF_303099 Mesorhizobium japonicum MAFF 303099]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEQ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5PN:7-HYDROXY-6-METHYLFURO[3,4-C]PYRIDIN-3(1H)-ONE'>5PN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.279Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5PN:7-HYDROXY-6-METHYLFURO[3,4-C]PYRIDIN-3(1H)-ONE'>5PN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4keq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4keq OCA], [https://pdbe.org/4keq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4keq RCSB], [https://www.ebi.ac.uk/pdbsum/4keq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4keq ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PDLA_RHILO PDLA_RHILO] Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Hydrolyzes 4-pyridoxolactone to 4-pyridoxic acid. Has lower activity toward N-hexanoyl-D,L-homoserine lactone, but is not active toward 5-pyridoxolactone and gamma-butyrolactone. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 25: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baba | [[Category: Mesorhizobium japonicum MAFF 303099]] | ||
[[Category: Kobayashi | [[Category: Baba S]] | ||
[[Category: Mikami | [[Category: Kobayashi J]] | ||
[[Category: Mizutani | [[Category: Mikami B]] | ||
[[Category: Takahashi | [[Category: Mizutani K]] | ||
[[Category: Yagi | [[Category: Takahashi N]] | ||
[[Category: Yoshikane | [[Category: Yagi T]] | ||
[[Category: Yoshikane Y]] | |||
Latest revision as of 14:29, 8 November 2023
Crystal structure of 4-pyridoxolactonase, 5-pyridoxolactone bound
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