5u0k: Difference between revisions

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<StructureSection load='5u0k' size='340' side='right'caption='[[5u0k]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='5u0k' size='340' side='right'caption='[[5u0k]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5u0k]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U0K FirstGlance]. <br>
<table><tr><td colspan='2'>[[5u0k]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U0K FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u0i|5u0i]], [[5u0j|5u0j]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.548&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS2, GA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0k OCA], [https://pdbe.org/5u0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u0k RCSB], [https://www.ebi.ac.uk/pdbsum/5u0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0k ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0k OCA], [http://pdbe.org/5u0k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u0k RCSB], [http://www.ebi.ac.uk/pdbsum/5u0k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLSL_HUMAN GLSL_HUMAN]] Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.<ref>PMID:20378837</ref>
[https://www.uniprot.org/uniprot/GLSL_HUMAN GLSL_HUMAN] Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.<ref>PMID:20378837</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glutaminase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ambrosio, A L.B]]
[[Category: Ambrosio ALB]]
[[Category: Dias, S M.G]]
[[Category: Dias SMG]]
[[Category: Ferreira, I M]]
[[Category: Ferreira IM]]
[[Category: Gonzalez, A]]
[[Category: Gonzalez A]]
[[Category: Pasquali, C C]]
[[Category: Pasquali CC]]
[[Category: Ankyrin]]
[[Category: Gls2]]
[[Category: Hydrolase]]
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