6bwg: Difference between revisions

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<StructureSection load='6bwg' size='340' side='right'caption='[[6bwg]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='6bwg' size='340' side='right'caption='[[6bwg]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6bwg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BWG FirstGlance]. <br>
<table><tr><td colspan='2'>[[6bwg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BWG FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cofC, Rv2983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-phospho-L-lactate_guanylyltransferase 2-phospho-L-lactate guanylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.68 2.7.7.68] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwg OCA], [https://pdbe.org/6bwg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bwg RCSB], [https://www.ebi.ac.uk/pdbsum/6bwg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwg OCA], [http://pdbe.org/6bwg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwg RCSB], [http://www.ebi.ac.uk/pdbsum/6bwg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COFC_MYCTU COFC_MYCTU]] Guanylyltransferase that catalyzes the activation of 2-phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.  
[https://www.uniprot.org/uniprot/FBID_MYCTU FBID_MYCTU] Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.[HAMAP-Rule:MF_02114]<ref>PMID:30952857</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2-phospho-L-lactate guanylyltransferase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Baker, E N]]
[[Category: Baker EN]]
[[Category: Jirgis, E N.M]]
[[Category: Bashiri G]]
[[Category: Alpha/beta structure]]
[[Category: Jirgis ENM]]
[[Category: Transferase]]

Latest revision as of 14:24, 13 March 2024

Crystal structure of native Rv2983 from Mycobacterium tuberculosis

6bwg, resolution 1.99Å

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