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New page: left|200px<br /> <applet load="1ctf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ctf, resolution 1.7Å" /> '''STRUCTURE OF THE C-T...
 
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[[Image:1ctf.gif|left|200px]]<br />
<applet load="1ctf" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1ctf, resolution 1.7&Aring;" />
'''STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS'''<br />


==Overview==
==STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS==
The structure of a C-terminal fragment of the ribosomal protein L7/L12, from Escherichia coli has been refined using crystallographic data to 1.7, A resolution. The R-value is 17.4%. Six residues at the N terminus are too, disordered in the structure to be localized. These residues are probably, part of a hinge in the complete L7/L12 molecule. The possibility that a, 2-fold crystallographic axis is a molecular 2-fold axis is discussed. A, patch of invariant residues on the surface of the dimer is probably, involved in functional interactions with elongation factors.
<StructureSection load='1ctf' size='340' side='right'caption='[[1ctf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ctf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CTF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ctf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ctf OCA], [https://pdbe.org/1ctf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ctf RCSB], [https://www.ebi.ac.uk/pdbsum/1ctf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ctf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL7_ECOLI RL7_ECOLI] Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation.[HAMAP-Rule:MF_00368]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ct/1ctf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ctf ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
1CTF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1CTF OCA].
*[[Ribosomal protein L7/L12|Ribosomal protein L7/L12]]
 
__TOC__
==Reference==
</StructureSection>
Structure of the C-terminal domain of the ribosomal protein L7/L12 from Escherichia coli at 1.7 A., Leijonmarck M, Liljas A, J Mol Biol. 1987 Jun 5;195(3):555-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3309338 3309338]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Leijonmarck, M.]]
[[Category: Leijonmarck M]]
[[Category: Liljas, A.]]
[[Category: Liljas A]]
[[Category: SO4]]
[[Category: ribosomal protein]]
 
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Retrieved from "https://proteopedia.org/1ctf"