6o0w: Difference between revisions

<table><tr><td colspan='2'>[[6o0w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_rotundifolia Vitis rotundifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O0W FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o0w OCA], [https://pdbe.org/6o0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o0w RCSB], [https://www.ebi.ac.uk/pdbsum/6o0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o0w ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RUN1_VITRO RUN1_VITRO] Disease resistance (R) protein that confers resistance to multiple powdery and downy mildew by promoting cell death (PubMed:24033846, PubMed:31439792). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792). Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:31439792).<ref>PMID:24033846</ref> <ref>PMID:31439792</ref>  

[[Category: Vitis rotundifolia]]

[[Category: Boden M]]

[[Category: Bosanac T]]

[[Category: Burdett H]]

[[Category: Casey L]]

[[Category: Chen J]]

[[Category: Coleman MP]]

[[Category: Dodds PN]]

[[Category: Dry IB]]

[[Category: Ericsson DJ]]

[[Category: Foley G]]

[[Category: Gilley J]]

[[Category: Gu W]]

[[Category: Horsefield S]]

[[Category: Hughes RO]]

[[Category: Kobe B]]

[[Category: Lai J]]

[[Category: Manik MK]]

[[Category: Nanson JD]]

[[Category: Rank M]]

[[Category: Rathjen JP]]

[[Category: Shi Y]]

[[Category: Staskawicz BJ]]

[[Category: Tiancong Q]]

[[Category: Ve T]]

[[Category: Williams SJ]]

[[Category: Zhang X]]

[[Category: Von Itzstein M]]