6vgk: Difference between revisions
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==ClpP1P2 complex from M. tuberculosis== | |||
<StructureSection load='6vgk' size='340' side='right'caption='[[6vgk]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6vgk]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VGK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vgk OCA], [https://pdbe.org/6vgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vgk RCSB], [https://www.ebi.ac.uk/pdbsum/6vgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vgk ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CLPP2_MYCTU CLPP2_MYCTU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). Degrades anti-sigma-D factor RsdA when present in a complex with ClpP1 and ClpX. Degrades anti-sigma-E factor RseA in the presence of ClpC1. Does not seem to act on anti-sigma-L factor RslA.[HAMAP-Rule:MF_00444]<ref>PMID:20025669</ref> <ref>PMID:23314154</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Kay LE]] | |||
[[Category: Ripstein ZA]] | |||
[[Category: Rubinstein JL]] | |||
[[Category: Vahidi S]] | |||
Latest revision as of 14:37, 6 March 2024
ClpP1P2 complex from M. tuberculosis
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