1hez: Difference between revisions

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==antibody-antigen complex==
==Structure of P. magnus protein L bound to a human IgM Fab.==
<StructureSection load='1hez' size='340' side='right'caption='[[1hez]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1hez' size='340' side='right'caption='[[1hez]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1hez]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Finegoldia_magna Finegoldia magna] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HEZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1hez]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna Finegoldia magna] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HEZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hez OCA], [http://pdbe.org/1hez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hez RCSB], [http://www.ebi.ac.uk/pdbsum/1hez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hez ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hez OCA], [https://pdbe.org/1hez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hez RCSB], [https://www.ebi.ac.uk/pdbsum/1hez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hez ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref>
== Function ==
[https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/he/1hez_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/he/1hez_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bottomley, S P]]
[[Category: Bottomley SP]]
[[Category: Charbonnier, J B]]
[[Category: Charbonnier JB]]
[[Category: Gore, M G]]
[[Category: Gore MG]]
[[Category: Graille, M]]
[[Category: Graille M]]
[[Category: Housden, N G]]
[[Category: Housden NG]]
[[Category: Stura, E A]]
[[Category: Stura EA]]
[[Category: Sutton, B J]]
[[Category: Sutton BJ]]
[[Category: Taussig, M J]]
[[Category: Taussig MJ]]
[[Category: Antibody]]
[[Category: Superantigen]]
Retrieved from "https://proteopedia.org/1hez"