6xvt: Difference between revisions
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==ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDDL-NH2== | |||
<StructureSection load='6xvt' size='340' side='right'caption='[[6xvt]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6xvt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XVT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2L5:2-CHLORO-L-PHENYLALANINE'>2L5</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NME:METHYLAMINE'>NME</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xvt OCA], [https://pdbe.org/6xvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xvt RCSB], [https://www.ebi.ac.uk/pdbsum/6xvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xvt ProSAT]</span></td></tr> | ||
[[Category: Le Cong | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/ENAH_HUMAN ENAH_HUMAN] Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity).<ref>PMID:11696321</ref> <ref>PMID:18158903</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Barone M]] | |||
[[Category: Le Cong K]] | |||
[[Category: Roske Y]] | |||
Latest revision as of 07:50, 7 February 2024
ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDDL-NH2
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