2bcs: Difference between revisions

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<StructureSection load='2bcs' size='340' side='right'caption='[[2bcs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2bcs' size='340' side='right'caption='[[2bcs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bcs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bcs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bcq|2bcq]], [[2bcr|2bcr]], [[2bcu|2bcu]], [[2bcv|2bcv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcs OCA], [http://pdbe.org/2bcs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bcs RCSB], [http://www.ebi.ac.uk/pdbsum/2bcs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcs OCA], [https://pdbe.org/2bcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcs RCSB], [https://www.ebi.ac.uk/pdbsum/2bcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bebenek, K]]
[[Category: Bebenek K]]
[[Category: Garcia-Diaz, M]]
[[Category: Garcia-Diaz M]]
[[Category: Krahn, J M]]
[[Category: Krahn JM]]
[[Category: Kunkel, T A]]
[[Category: Kunkel TA]]
[[Category: Pedersen, L C]]
[[Category: Pedersen LC]]
[[Category: Deletion]]
[[Category: Extrahelical]]
[[Category: Lyase-dna complex]]
[[Category: Misalignment]]
[[Category: Mutagenesis]]
[[Category: Mutation]]
[[Category: Slippage]]
[[Category: Streisinger]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/2bcs"