2bjc: Difference between revisions

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==NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor==
==NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor==
<StructureSection load='2bjc' size='340' side='right'caption='[[2bjc]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''>
<StructureSection load='2bjc' size='340' side='right'caption='[[2bjc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bjc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BJC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bjc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BJC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cjg|1cjg]], [[1efa|1efa]], [[1jwl|1jwl]], [[1jye|1jye]], [[1jyf|1jyf]], [[1l1m|1l1m]], [[1lbg|1lbg]], [[1lbh|1lbh]], [[1lbi|1lbi]], [[1lcc|1lcc]], [[1lcd|1lcd]], [[1lqc|1lqc]], [[1ltp|1ltp]], [[1osl|1osl]], [[1tlf|1tlf]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 16 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bjc OCA], [http://pdbe.org/2bjc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bjc RCSB], [http://www.ebi.ac.uk/pdbsum/2bjc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bjc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bjc OCA], [https://pdbe.org/2bjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bjc RCSB], [https://www.ebi.ac.uk/pdbsum/2bjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bjc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI]] Repressor of the lactose operon. Binds allolactose as an inducer.  
[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/2bjc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/2bjc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boelens, R]]
[[Category: Boelens R]]
[[Category: Bonvin, A M.J J]]
[[Category: Bonvin AMJJ]]
[[Category: Das, D]]
[[Category: Das D]]
[[Category: Folkers, G E]]
[[Category: Folkers GE]]
[[Category: Kaptein, R]]
[[Category: Kaptein R]]
[[Category: Salinas, R K]]
[[Category: Salinas RK]]
[[Category: Altered specificity]]
[[Category: Dna-binding]]
[[Category: Gal operon]]
[[Category: Gal repressor]]
[[Category: Hth]]
[[Category: Lac headpiece]]
[[Category: Lac operon]]
[[Category: Lac repressor]]
[[Category: Mutant]]
[[Category: Repressor]]
[[Category: Symmetric dimer]]
[[Category: Symmetric dna-binding]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
[[Category: Transcription regulator/dna]]
Retrieved from "https://proteopedia.org/2bjc"