6vw2: Difference between revisions
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New page: '''Unreleased structure''' The entry 6vw2 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils== | |||
<StructureSection load='6vw2' size='340' side='right'caption='[[6vw2]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6vw2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VW2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vw2 OCA], [https://pdbe.org/6vw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vw2 RCSB], [https://www.ebi.ac.uk/pdbsum/6vw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vw2 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.[https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Boyer DR]] | |||
[[Category: Cao Q]] | |||
[[Category: Eisenberg DS]] | |||
[[Category: Sawaya MR]] | |||