5r4j: Difference between revisions
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New page: '''Unreleased structure''' The entry 5r4j is ON HOLD Authors: Talon, R., Krojer, T., Fairhead, M., Sethi, R., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., W... |
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==PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000280a== | |||
<StructureSection load='5r4j' size='340' side='right'caption='[[5r4j]], [[Resolution|resolution]] 1.39Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5r4j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R4J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RUY:4-piperidin-1-yl-1,2,5-oxadiazol-3-amine'>RUY</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
[[Category: Aimon | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4j OCA], [https://pdbe.org/5r4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r4j RCSB], [https://www.ebi.ac.uk/pdbsum/5r4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4j ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Aimon A]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Bradley AR]] | ||
[[Category: | [[Category: Brandao-Neto J]] | ||
[[Category: | [[Category: Brennan PE]] | ||
[[Category: | [[Category: Collins P]] | ||
[[Category: | [[Category: Dias A]] | ||
[[Category: | [[Category: Douangamath A]] | ||
[[Category: | [[Category: Edwards A]] | ||
[[Category: Fairhead M]] | |||
[[Category: Krojer T]] | |||
[[Category: MacLean E]] | |||
[[Category: Renjie Z]] | |||
[[Category: Sethi R]] | |||
[[Category: Talon R]] | |||
[[Category: Wright N]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 13:01, 18 February 2026
PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000280a
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