5ijo: Difference between revisions

<table><tr><td colspan='2'>[[5ijo]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IJO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IJO FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUP155, KIAA0791 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP93, KIAA0095 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP205, C7orf14, KIAA0225 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP54 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP58, KIAA0410, NUPL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP62 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), NUP188, KIAA0169 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ijo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ijo OCA], [http://pdbe.org/5ijo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ijo RCSB], [http://www.ebi.ac.uk/pdbsum/5ijo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ijo ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/NUP62_HUMAN NUP62_HUMAN]] Familial infantile bilateral striatal necrosis. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN]] Familial atrial fibrillation. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/NU188_HUMAN NU188_HUMAN]] Copy number variations of NUP188 gene may be a cause of heterotaxy, a congenital heart disease resulting from abnormalities in left-right (LR) body patterning.<ref>PMID:21282601</ref>

[[http://www.uniprot.org/uniprot/NUP62_HUMAN NUP62_HUMAN]] Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex. [[http://www.uniprot.org/uniprot/NUP54_HUMAN NUP54_HUMAN]] Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. [[http://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN]] Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.[UniProtKB:Q99P88] [[http://www.uniprot.org/uniprot/NU205_HUMAN NU205_HUMAN]] Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC.<ref>PMID:15229283</ref>  [[http://www.uniprot.org/uniprot/NU188_HUMAN NU188_HUMAN]] May function as a component of the nuclear pore complex (NPC). [[http://www.uniprot.org/uniprot/NUP93_HUMAN NUP93_HUMAN]] Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.<ref>PMID:15229283</ref> <ref>PMID:15703211</ref>  [[http://www.uniprot.org/uniprot/NUP58_HUMAN NUP58_HUMAN]] Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.  

[[Category: Human]]

[[Category: Beck, M]]

[[Category: Kosinski, J]]

[[Category: Mosalaganti, S]]

[[Category: Nuclear pore complex]]

[[Category: Transport protein]]