4cau: Difference between revisions

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<SX load='4cau' size='340' side='right' viewer='molstar' caption='[[4cau]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
<SX load='4cau' size='340' side='right' viewer='molstar' caption='[[4cau]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cau]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CAU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cau]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CAU FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cau OCA], [http://pdbe.org/4cau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cau RCSB], [http://www.ebi.ac.uk/pdbsum/4cau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cau ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cau OCA], [https://pdbe.org/4cau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cau RCSB], [https://www.ebi.ac.uk/pdbsum/4cau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cau ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q689G3_9FLAV Q689G3_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]  
[https://www.uniprot.org/uniprot/Q689G3_9FLAV Q689G3_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Alonso, S]]
[[Category: Alonso S]]
[[Category: Aung, M]]
[[Category: Aung M]]
[[Category: Chan, A H]]
[[Category: Chan AH]]
[[Category: Chan, S H]]
[[Category: Chan SH]]
[[Category: Fisher, D]]
[[Category: Fisher D]]
[[Category: Hanson, B J]]
[[Category: Hanson BJ]]
[[Category: Kemeny, D M]]
[[Category: Kemeny DM]]
[[Category: Kostyuchenko, V A]]
[[Category: Kostyuchenko VA]]
[[Category: Kukkaro, P]]
[[Category: Kukkaro P]]
[[Category: Leo, Y S]]
[[Category: Leo YS]]
[[Category: Lim, A P]]
[[Category: Lim AP]]
[[Category: Lok, S M]]
[[Category: Lok SM]]
[[Category: Macary, P A]]
[[Category: Macary PA]]
[[Category: Ng, J K]]
[[Category: Ng JK]]
[[Category: Ng, M L]]
[[Category: Ng ML]]
[[Category: Ooi, E E]]
[[Category: Ooi EE]]
[[Category: Schul, W]]
[[Category: Schul W]]
[[Category: Shi, P Y]]
[[Category: Shi PY]]
[[Category: Smith, K G]]
[[Category: Smith KG]]
[[Category: Tan, G K]]
[[Category: Tan GK]]
[[Category: Tan, T T]]
[[Category: Tan TT]]
[[Category: Teo, E W]]
[[Category: Teo EW]]
[[Category: Teoh, E P]]
[[Category: Teoh EP]]
[[Category: Yip, A]]
[[Category: Yip A]]
[[Category: Zou, G]]
[[Category: Zou G]]
[[Category: Antibody]]
[[Category: Flavivirus]]
[[Category: Hmab]]
[[Category: Human antibody]]
[[Category: Mature virus]]
[[Category: Monoclonal antibody]]
[[Category: Serotype 1]]
[[Category: Virus]]
Retrieved from "https://proteopedia.org/4cau"