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<SX load='6ilj' size='340' side='right' viewer='molstar' caption='[[6ilj]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<SX load='6ilj' size='340' side='right' viewer='molstar' caption='[[6ilj]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ilj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Echovirus_e6 Echovirus e6] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ILJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ILJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ilj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E6 Echovirus E6] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ILJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ILJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD55, CR, DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ilj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ilj OCA], [http://pdbe.org/6ilj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ilj RCSB], [http://www.ebi.ac.uk/pdbsum/6ilj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ilj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ilj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ilj OCA], [https://pdbe.org/6ilj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ilj RCSB], [https://www.ebi.ac.uk/pdbsum/6ilj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ilj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref> 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ilj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ilj" style="background-color:#fffaf0;"></div>
==See Also==
*[[CD55|CD55]]
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</SX>
</SX>
[[Category: Echovirus e6]]
[[Category: Echovirus E6]]
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gao, G F]]
[[Category: Gao GF]]
[[Category: Liu, S]]
[[Category: Liu S]]
[[Category: Peng, R]]
[[Category: Peng R]]
[[Category: Zhao, X]]
[[Category: Zhao X]]
[[Category: Cd55]]
[[Category: Cryo-em]]
[[Category: Echovirus 6]]
[[Category: Virus]]
[[Category: Virus-receptor complex]]
Retrieved from "https://proteopedia.org/6ilj"