6rtc: Difference between revisions
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<SX load='6rtc' size='340' side='right' viewer='molstar' caption='[[6rtc]], [[Resolution|resolution]] 3.96Å' scene=''> | <SX load='6rtc' size='340' side='right' viewer='molstar' caption='[[6rtc]], [[Resolution|resolution]] 3.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6rtc]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6rtc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RTC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.96Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rtc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rtc OCA], [https://pdbe.org/6rtc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rtc RCSB], [https://www.ebi.ac.uk/pdbsum/6rtc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rtc ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/S26A9_MOUSE S26A9_MOUSE] Ion transporter that can act both as an ion channel and anion exchanger (PubMed:15800055, PubMed:17120765, PubMed:31339488). Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane (PubMed:31339488). Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane (PubMed:15800055).<ref>PMID:15800055</ref> <ref>PMID:17120765</ref> <ref>PMID:31339488</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</SX> | </SX> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Dutzler | [[Category: Dutzler R]] | ||
[[Category: Sawicka | [[Category: Sawicka M]] | ||
[[Category: Walter | [[Category: Walter JD]] | ||