6m52: Difference between revisions
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==Human apo ferritin frozen on TEM grid with amorphous carbon supporting film== | |||
<StructureSection load='6m52' size='340' side='right'caption='[[6m52]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6m52]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M52 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m52 OCA], [https://pdbe.org/6m52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m52 RCSB], [https://www.ebi.ac.uk/pdbsum/6m52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m52 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
==See Also== | |||
*[[Ferritin 3D structures|Ferritin 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Huang | [[Category: Chen H]] | ||
[[Category: Ji | [[Category: Huang X]] | ||
[[Category: | [[Category: Ji G]] | ||
[[Category: | [[Category: Li S]] | ||
[[Category: | [[Category: Sun F]] | ||
[[Category: | [[Category: Wen Z]] | ||
[[Category: Yin C]] | |||
[[Category: Zhang L]] | |||