5c04: Difference between revisions

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<StructureSection load='5c04' size='340' side='right'caption='[[5c04]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5c04' size='340' side='right'caption='[[5c04]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5c04]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C04 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C04 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5c04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C04 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x0x|4x0x]], [[4x1u|4x1u]], [[4xih|4xih]], [[1xxu|1xxu]], [[1xvw|1xvw]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2298 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c04 OCA], [https://pdbe.org/5c04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c04 RCSB], [https://www.ebi.ac.uk/pdbsum/5c04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c04 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c04 OCA], [http://pdbe.org/5c04 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c04 RCSB], [http://www.ebi.ac.uk/pdbsum/5c04 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c04 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AHPE_MYCTU AHPE_MYCTU] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May represent an important antioxidant defense against cytotoxic peroxides, especially peroxynitrite, which can be formed by activated macrophages during infection.<ref>PMID:19737009</ref> <ref>PMID:24379404</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Peroxiredoxin]]
[[Category: Dufe, V T]]
[[Category: Messens, J]]
[[Category: Pallo, A]]
[[Category: 1-cys peroxiredoxin]]
[[Category: Active site mutant]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Oxidoreductase]]
[[Category: Dufe VT]]
[[Category: Thioredoxin fold]]
[[Category: Messens J]]
[[Category: Pallo A]]
Retrieved from "https://proteopedia.org/5c04"