6vo6: Difference between revisions
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==Crystal Structure of Cj1427, an Essential NAD-dependent Dehydrogenase from Campylobacter jejuni, in the Presence of NADH and GDP== | |||
<StructureSection load='6vo6' size='340' side='right'caption='[[6vo6]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6vo6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VO6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=TMA:TETRAMETHYLAMMONIUM+ION'>TMA</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vo6 OCA], [https://pdbe.org/6vo6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vo6 RCSB], [https://www.ebi.ac.uk/pdbsum/6vo6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vo6 ProSAT]</span></td></tr> | ||
[[Category: Anderson | </table> | ||
[[Category: Holden | == Function == | ||
[[Category: Huddleston | [https://www.uniprot.org/uniprot/GMHD_CAMJE GMHD_CAMJE] NAD-dependent dehydrogenase involved in the biosynthesis of heptose moieties with a hydroxyl group at C6 found on the capsular polysaccharide (CPS) of C.jejuni. Catalyzes the initial oxidation of C4 of the GDP-D-glycero-alpha-D-manno-heptose to form GDP-D-glycero-4-keto-alpha-D-lyxo-heptose in the presence of alpha-ketoglutarate required to recycle the NADH nucleotide.<ref>PMID:32168448</ref> | ||
[[Category: Spencer | == References == | ||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]] | |||
[[Category: Large Structures]] | |||
[[Category: Anderson TK]] | |||
[[Category: Holden HM]] | |||
[[Category: Huddleston JP]] | |||
[[Category: Raushel FM]] | |||
[[Category: Spencer KD]] | |||
[[Category: Thoden JB]] | |||
Latest revision as of 14:38, 6 March 2024
Crystal Structure of Cj1427, an Essential NAD-dependent Dehydrogenase from Campylobacter jejuni, in the Presence of NADH and GDP
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