6ln2: Difference between revisions

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<StructureSection load='6ln2' size='340' side='right'caption='[[6ln2]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='6ln2' size='340' side='right'caption='[[6ln2]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ln2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pasteurianus"_(winogradsky_1895)_lehmann_and_neumann_1907 "bacillus pasteurianus" (winogradsky 1895) lehmann and neumann 1907] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LN2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ln2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LN2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLP1R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1501 "Bacillus pasteurianus" (Winogradsky 1895) Lehmann and Neumann 1907])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ln2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ln2 OCA], [http://pdbe.org/6ln2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ln2 RCSB], [http://www.ebi.ac.uk/pdbsum/6ln2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ln2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ln2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ln2 OCA], [https://pdbe.org/6ln2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ln2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ln2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ln2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  
[https://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/RUBR_CLOPA RUBR_CLOPA] Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ln2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ln2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Glucagon-like peptide receptor 3D structures|Glucagon-like peptide receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clostridium pasteurianum]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Han, G W]]
[[Category: Han GW]]
[[Category: Hang, K]]
[[Category: Hang K]]
[[Category: Hanson, M]]
[[Category: Hanson M]]
[[Category: Jiang, H]]
[[Category: Jiang H]]
[[Category: Laursen, M]]
[[Category: Laursen M]]
[[Category: Lin, G]]
[[Category: Lin G]]
[[Category: Reedtz-Runge, S]]
[[Category: Reedtz-Runge S]]
[[Category: Ren, Q]]
[[Category: Ren Q]]
[[Category: Roed, N K]]
[[Category: Roed NK]]
[[Category: Song, G]]
[[Category: Song G]]
[[Category: Stevens, R C]]
[[Category: Stevens RC]]
[[Category: Wang, M]]
[[Category: Wang M]]
[[Category: Wu, F]]
[[Category: Wu F]]
[[Category: Wu, L]]
[[Category: Wu L]]
[[Category: Yang, L]]
[[Category: Yang L]]
[[Category: Class b]]
[[Category: Fab7f38]]
[[Category: Full length human glp1 receptor]]
[[Category: Lcp]]
[[Category: Membrane protein]]
[[Category: Nam pf06372222]]
[[Category: Tmd]]
Retrieved from "https://proteopedia.org/6ln2"