6ukj: Difference between revisions

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<SX load='6ukj' size='340' side='right' viewer='molstar' caption='[[6ukj]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<SX load='6ukj' size='340' side='right' viewer='molstar' caption='[[6ukj]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ukj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Plaf8 Plaf8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UKJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6UKJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ukj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_7G8 Plasmodium falciparum 7G8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UKJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFBG_01689 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=57266 PLAF8])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ukj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ukj OCA], [http://pdbe.org/6ukj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ukj RCSB], [http://www.ebi.ac.uk/pdbsum/6ukj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ukj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ukj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ukj OCA], [https://pdbe.org/6ukj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ukj RCSB], [https://www.ebi.ac.uk/pdbsum/6ukj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ukj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRT_PLAF8 CRT_PLAF8] Nutrient transporter (PubMed:25733858, PubMed:31776516, PubMed:32764664). Substrate transport is pH-dependent (PubMed:25733858, PubMed:31776516). Can transport arginine, lysine, histidine and peptides (PubMed:25733858, PubMed:31776516, PubMed:32764664). Involved in maintaining the osmotic homeostasis of the digestive vacuole (By similarity). Required for the normal asexual intraerythrocytic proliferation of parasites (By similarity).[UniProtKB:Q9N623]<ref>PMID:25733858</ref> <ref>PMID:31776516</ref> <ref>PMID:32764664</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Plaf8]]
[[Category: Plasmodium falciparum 7G8]]
[[Category: Carragher, B]]
[[Category: Carragher B]]
[[Category: Dhingra, S K]]
[[Category: Dhingra SK]]
[[Category: Erramilli, S K]]
[[Category: Erramilli SK]]
[[Category: Fidock, D A]]
[[Category: Fidock DA]]
[[Category: Giacometti, S I]]
[[Category: Giacometti SI]]
[[Category: Hagenah, L M]]
[[Category: Hagenah LM]]
[[Category: Kim, J]]
[[Category: Kim J]]
[[Category: Kossiakoff, A A]]
[[Category: Kossiakoff AA]]
[[Category: Mancia, F]]
[[Category: Mancia F]]
[[Category: Nosol, K]]
[[Category: Nosol K]]
[[Category: Okombo, J]]
[[Category: Okombo J]]
[[Category: Potter, C S]]
[[Category: Potter CS]]
[[Category: Quick, M]]
[[Category: Quick M]]
[[Category: Roepe, P D]]
[[Category: Roepe PD]]
[[Category: Tan, Y Z]]
[[Category: Tan YZ]]
[[Category: Vendome, J]]
[[Category: Vendome J]]
[[Category: Warren, A L]]
[[Category: Warren AL]]
[[Category: Wicht, K J]]
[[Category: Wicht KJ]]
[[Category: Digestive vacuole of malaria parasite]]
[[Category: Drug resistance]]
[[Category: Membrane protein]]
[[Category: Nanodisc]]
[[Category: Transporter]]
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