4d3e: Difference between revisions

<table><tr><td colspan='2'>[[4d3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_5a_str._M90T Shigella flexneri 5a str. M90T]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D3E FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.12&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d3e OCA], [https://pdbe.org/4d3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d3e RCSB], [https://www.ebi.ac.uk/pdbsum/4d3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d3e ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>  

[[Category: Shigella flexneri 5a str. M90T]]

[[Category: Blocker AJ]]

[[Category: Brown J]]

[[Category: Cheung M]]

[[Category: Frazer G]]

[[Category: Kato T]]

[[Category: Liu X]]

[[Category: Makino F]]

[[Category: Mantell J]]

[[Category: Martinez-Argudo I]]

[[Category: Mina P]]

[[Category: Murillo I]]

[[Category: Namba K]]

[[Category: Pain M]]

[[Category: Roehrich D]]

[[Category: Sessions RB]]

[[Category: Shen D-K]]

[[Category: Todd T]]

[[Category: Walker ML]]