5eyy: Difference between revisions
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<StructureSection load='5eyy' size='340' side='right'caption='[[5eyy]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5eyy' size='340' side='right'caption='[[5eyy]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5eyy]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5eyy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Centrolobium_tomentosum Centrolobium tomentosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EYY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand= | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.902Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eyy OCA], [https://pdbe.org/5eyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eyy RCSB], [https://www.ebi.ac.uk/pdbsum/5eyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eyy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LECC1_CENTO LECC1_CENTO] Mannose/glucose-specific lectin that also binds derivatives N-acetyl-D-glucosamine and alpha-methyl-D-mannopyranoside with even higher affinity (PubMed:26946944, Ref.2). Has hemagglutinating activity towards rabbit erythrocytes (Ref.2). Is toxic towards brine shrimp A.nauplii (Ref.2). In rats, induces dose-dependent paw edema (PubMed:26946944).<ref>PMID:26946944</ref> [REFERENCE:2] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Centrolobium tomentosum]] | [[Category: Centrolobium tomentosum]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Almeida | [[Category: Almeida AC]] | ||
[[Category: Almeida | [[Category: Almeida RPH]] | ||
[[Category: Cavada | [[Category: Cavada BS]] | ||
[[Category: Delatorre | [[Category: Delatorre P]] | ||
[[Category: Lossio | [[Category: Lossio CF]] | ||
[[Category: Nascimento | [[Category: Nascimento KS]] | ||
[[Category: Osterne | [[Category: Osterne VJS]] | ||
[[Category: Pinto-Junior | [[Category: Pinto-Junior VR]] | ||
[[Category: Rocha | [[Category: Rocha BAM]] | ||
[[Category: Santiago | [[Category: Santiago MQ]] | ||
[[Category: Silva-Filho | [[Category: Silva-Filho JC]] | ||
[[Category: Teixeira | [[Category: Teixeira CS]] | ||
Latest revision as of 08:52, 23 October 2024
Tetragonal Form of Centrolobium tomentosum seed lectin (CTL) complexed with Man1-3Man-OMe.
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