6wpq: Difference between revisions
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The entry | ==GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant== | ||
<StructureSection load='6wpq' size='340' side='right'caption='[[6wpq]], [[Resolution|resolution]] 1.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6wpq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WPQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wpq OCA], [https://pdbe.org/6wpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wpq RCSB], [https://www.ebi.ac.uk/pdbsum/6wpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wpq ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Boyer DR]] | |||
[[Category: Cao Q]] | |||
[[Category: Cascio D]] | |||
[[Category: Eisenberg DS]] | |||
[[Category: Hughes MP]] | |||
[[Category: Lu J]] | |||
[[Category: Sawaya MR]] | |||
Latest revision as of 14:46, 6 March 2024
GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant
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