5ncm: Difference between revisions

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<StructureSection load='5ncm' size='340' side='right'caption='[[5ncm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5ncm' size='340' side='right'caption='[[5ncm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ncm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NCM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ncm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NCM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MOB2, YFL034C-B, YFL035C, YFL035C-A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824]), CBK1, YNL161W, N1727 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ncm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ncm OCA], [https://pdbe.org/5ncm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ncm RCSB], [https://www.ebi.ac.uk/pdbsum/5ncm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ncm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ncm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ncm OCA], [http://pdbe.org/5ncm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ncm RCSB], [http://www.ebi.ac.uk/pdbsum/5ncm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ncm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MOB2_YEAST MOB2_YEAST]] Functions as an activator subunit for the CBK1 protein kinase. Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network. Required for coordinating polarized cell growth during interphase with the onset of mitosis. Required for mother/daughter cell separation after cytokinesis. Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit. It coordinates ACE2-dependent transcription with mitotic exit network activation.<ref>PMID:11747810</ref> <ref>PMID:12196508</ref> [[http://www.uniprot.org/uniprot/CBK1_YEAST CBK1_YEAST]] Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
[https://www.uniprot.org/uniprot/MOB2_YEAST MOB2_YEAST] Functions as an activator subunit for the CBK1 protein kinase. Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network. Required for coordinating polarized cell growth during interphase with the onset of mitosis. Required for mother/daughter cell separation after cytokinesis. Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit. It coordinates ACE2-dependent transcription with mitotic exit network activation.<ref>PMID:11747810</ref> <ref>PMID:12196508</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Gogl, G]]
[[Category: Gogl G]]
[[Category: Parker, B]]
[[Category: Parker B]]
[[Category: Remenyi, A]]
[[Category: Remenyi A]]
[[Category: Weiss, E]]
[[Category: Weiss E]]
[[Category: Kinase]]
[[Category: Signaling protein]]
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