6u7m: Difference between revisions

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<StructureSection load='6u7m' size='340' side='right'caption='[[6u7m]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
<StructureSection load='6u7m' size='340' side='right'caption='[[6u7m]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6u7m]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U7M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6U7M FirstGlance]. <br>
<table><tr><td colspan='2'>[[6u7m]] is a 30 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6U7M FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lipoprotein_lipase Lipoprotein lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.34 3.1.1.34] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6u7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u7m OCA], [http://pdbe.org/6u7m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u7m RCSB], [http://www.ebi.ac.uk/pdbsum/6u7m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u7m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6u7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u7m OCA], [https://pdbe.org/6u7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6u7m RCSB], [https://www.ebi.ac.uk/pdbsum/6u7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6u7m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LIPL_BOVIN LIPL_BOVIN]] Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed:9188470).[UniProtKB:P06858]<ref>PMID:9188470</ref>
[https://www.uniprot.org/uniprot/LIPL_BOVIN LIPL_BOVIN] Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed:9188470).[UniProtKB:P06858]<ref>PMID:9188470</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6u7m" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6u7m" style="background-color:#fffaf0;"></div>
==See Also==
*[[Lipase 3D Structures|Lipase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lipoprotein lipase]]
[[Category: Egelman EH]]
[[Category: Egelman, E H]]
[[Category: Gunn KH]]
[[Category: Gunn, K H]]
[[Category: Neher SB]]
[[Category: Neher, S B]]
[[Category: Wang F]]
[[Category: Wang, F]]
[[Category: Helical symmetry]]
[[Category: Hydrolase]]
[[Category: Protein fibril]]
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