6wsm: Difference between revisions
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==Crystal structure of coiled coil region of human septin 8== | |||
<StructureSection load='6wsm' size='340' side='right'caption='[[6wsm]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6wsm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WSM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.451Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wsm OCA], [https://pdbe.org/6wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wsm RCSB], [https://www.ebi.ac.uk/pdbsum/6wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wsm ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SEPT8_HUMAN SEPT8_HUMAN] Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (PubMed:15116257). Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).[UniProtKB:B0BNF1]<ref>PMID:15116257</ref> Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP.<ref>PMID:27084579</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Valadares | [[Category: Large Structures]] | ||
[[Category: Araujo APU]] | |||
[[Category: Brandao-Neto J]] | |||
[[Category: Cabrejos DAL]] | |||
[[Category: Cavini I]] | |||
[[Category: Garratt RC]] | |||
[[Category: Nascimento AFZ]] | |||
[[Category: Pereira HM]] | |||
[[Category: Sala FA]] | |||
[[Category: Uson I]] | |||
[[Category: Valadares NF]] | |||
Latest revision as of 14:46, 6 March 2024
Crystal structure of coiled coil region of human septin 8
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