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==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)==
==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)==
<StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]]' scene=''>
<StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br>
<table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [http://pdbe.org/6s4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [http://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith CH]]
Retrieved from "https://proteopedia.org/6s4m"