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==NMR solution structure of the double GS-Tamapin mutation R6A/R7A==
==NMR solution structure of the double GS-Tamapin mutation R6A/R7A==
<StructureSection load='2meo' size='340' side='right'caption='[[2meo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2meo' size='340' side='right'caption='[[2meo]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2meo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_tamalus Buthus tamalus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MEO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MEO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2meo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_tamulus Mesobuthus tamulus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MEO FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2me7|2me7]], [[2mel|2mel]], [[2men|2men]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2meo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2meo OCA], [http://pdbe.org/2meo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2meo RCSB], [http://www.ebi.ac.uk/pdbsum/2meo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2meo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2meo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2meo OCA], [https://pdbe.org/2meo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2meo RCSB], [https://www.ebi.ac.uk/pdbsum/2meo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2meo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/KAX54_MESTA KAX54_MESTA]] Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable selectivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.<ref>PMID:12239213</ref> 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buthus tamalus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ramirez-Cordero, B]]
[[Category: Mesobuthus tamulus]]
[[Category: Rio-Portilla, F del]]
[[Category: Ramirez-Cordero B]]
[[Category: Alpha ktx5 4 double mutant r6a r7a]]
[[Category: Del Rio-Portilla F]]
[[Category: Scorpion toxin]]
[[Category: Tamapin]]
[[Category: Toxin]]
Retrieved from "https://proteopedia.org/2meo"