5gns: Difference between revisions

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<StructureSection load='5gns' size='340' side='right'caption='[[5gns]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5gns' size='340' side='right'caption='[[5gns]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5gns]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GNS FirstGlance]. <br>
<table><tr><td colspan='2'>[[5gns]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GNS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.702&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gnt|5gnt]], [[5gnr|5gnr]], [[5gnu|5gnu]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MFN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gns OCA], [https://pdbe.org/5gns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gns RCSB], [https://www.ebi.ac.uk/pdbsum/5gns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gns ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gns OCA], [http://pdbe.org/5gns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gns RCSB], [http://www.ebi.ac.uk/pdbsum/5gns PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gns ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN]] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref>
[https://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Guo, X]]
[[Category: Guo X]]
[[Category: Hu, J]]
[[Category: Hu J]]
[[Category: Hu, X]]
[[Category: Hu X]]
[[Category: Huang, X]]
[[Category: Huang X]]
[[Category: Lou, Z]]
[[Category: Lou Z]]
[[Category: Qi, Y]]
[[Category: Qi Y]]
[[Category: Rao, Z]]
[[Category: Rao Z]]
[[Category: Yan, L]]
[[Category: Yan L]]
[[Category: Yu, C]]
[[Category: Yu C]]
[[Category: Zhou, X]]
[[Category: Zhou X]]
[[Category: Bdlp-like folding]]
[[Category: Hydrolase]]
[[Category: Mitofusin 1]]