5hbu: Difference between revisions

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<StructureSection load='5hbu' size='340' side='right'caption='[[5hbu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5hbu' size='340' side='right'caption='[[5hbu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hbu]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HBU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HBU FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hbu]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HBU FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5haw|5haw]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">slmA, ttk, yicB, b3641, JW5641 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hbu OCA], [https://pdbe.org/5hbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hbu RCSB], [https://www.ebi.ac.uk/pdbsum/5hbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hbu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hbu OCA], [http://pdbe.org/5hbu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hbu RCSB], [http://www.ebi.ac.uk/pdbsum/5hbu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hbu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SLMA_ECOLI SLMA_ECOLI]] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.[HAMAP-Rule:MF_01839]<ref>PMID:15916962</ref> <ref>PMID:21113127</ref> <ref>PMID:21321206</ref> 
[https://www.uniprot.org/uniprot/FTSZ_ECOLI FTSZ_ECOLI] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. Polymerization and bundle formation is enhanced by CbeA.[HAMAP-Rule:MF_00909]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Schumacher, M A]]
[[Category: Synthetic construct]]
[[Category: Zeng, W]]
[[Category: Schumacher MA]]
[[Category: Cell cycle-dna complex]]
[[Category: Zeng W]]
[[Category: Cytokinesis]]
[[Category: Ftsz]]
[[Category: Nucleoid occlusion]]
[[Category: Slma]]
Retrieved from "https://proteopedia.org/5hbu"