6z2h: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6z2h is ~~ON HOLD~~

==Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.==

== Structural highlights ==

<table><tr><td colspan='2'>[[6z2h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z2H OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6Z2H FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=Q5B:(3S)-citryl-Coenzyme+A'>Q5B</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6z2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z2h OCA], [https://pdbe.org/6z2h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z2h RCSB], [https://www.ebi.ac.uk/pdbsum/6z2h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z2h ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>

~~Authors~~:

==See Also==

*[[ATP-citrate synthase 3D structures|ATP-citrate synthase 3D structures]]

~~Description~~:

== References ==

[[Category: ~~Unreleased Structures~~]]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Verschueren KHG]]

[[Category: Verstraete K]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6z2h is ON HOLD
+==Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.==
+<StructureSection load='6z2h' size='340' side='right'caption='[[6z2h]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6z2h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z2H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z2H FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=Q5B:(3S)-citryl-Coenzyme+A'>Q5B</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z2h OCA], [https://pdbe.org/6z2h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z2h RCSB], [https://www.ebi.ac.uk/pdbsum/6z2h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z2h ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>
-Authors:
+==See Also==
+*[[ATP-citrate synthase 3D structures|ATP-citrate synthase 3D structures]]
-Description:
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Verschueren KHG]]
+[[Category: Verstraete K]]