6x4s: Difference between revisions
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New page: '''Unreleased structure''' The entry 6x4s is ON HOLD Authors: Description: Category: Unreleased Structures |
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==MCU-EMRE complex of a metazoan mitochondrial calcium uniporter== | |||
<StructureSection load='6x4s' size='340' side='right'caption='[[6x4s]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6x4s]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tribolium_castaneum Tribolium castaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X4S FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x4s OCA], [https://pdbe.org/6x4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x4s RCSB], [https://www.ebi.ac.uk/pdbsum/6x4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x4s ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/D6X268_TRICA D6X268_TRICA] Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.[RuleBase:RU369077][https://www.uniprot.org/uniprot/D6WIX5_TRICA D6WIX5_TRICA] Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[RuleBase:RU367035] | |||
==See Also== | |||
*[[Mitochondrial calcium uniporter|Mitochondrial calcium uniporter]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Tribolium castaneum]] | |||
[[Category: Baradaran R]] | |||
[[Category: Long SB]] | |||
[[Category: Wang C]] | |||
Latest revision as of 14:48, 6 March 2024
MCU-EMRE complex of a metazoan mitochondrial calcium uniporter
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