6wbl: Difference between revisions

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==n/a==
==Cryo-EM structure of human Pannexin 1 channel with deletion of N-terminal helix and C-terminal tail, in complex with CBX==
<StructureSection load='6wbl' size='340' side='right'caption='[[6wbl]]' scene=''>
<StructureSection load='6wbl' size='340' side='right'caption='[[6wbl]], [[Resolution|resolution]] 5.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WBL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WBL FirstGlance]. <br>
<table><tr><td colspan='2'>[[6wbl]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WBL FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wbl OCA], [http://pdbe.org/6wbl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wbl RCSB], [http://www.ebi.ac.uk/pdbsum/6wbl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wbl ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5.13&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wbl OCA], [https://pdbe.org/6wbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wbl RCSB], [https://www.ebi.ac.uk/pdbsum/6wbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wbl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref>
==See Also==
*[[Pannexin|Pannexin]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N/a]]
[[Category: Du J]]
[[Category: Lu W]]
[[Category: Ruan Z]]