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<StructureSection load='5ign' size='340' side='right'caption='[[5ign]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5ign' size='340' side='right'caption='[[5ign]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ign]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IGN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ign]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IGN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD9, UNQ3040/PRO9856 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [http://pdbe.org/5ign PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [http://www.ebi.ac.uk/pdbsum/5ign PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ign ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [https://pdbe.org/5ign PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [https://www.ebi.ac.uk/pdbsum/5ign PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ign ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription.  
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Brennan, P E]]
[[Category: Brennan PE]]
[[Category: Clark, P G.K]]
[[Category: Clark PGK]]
[[Category: Delft, F von]]
[[Category: Dixon DJ]]
[[Category: Dixon, D J]]
[[Category: Edwards AM]]
[[Category: Edwards, A M]]
[[Category: Fedorov O]]
[[Category: Fedorov, O]]
[[Category: Knapp S]]
[[Category: Knapp, S]]
[[Category: Krojer T]]
[[Category: Krojer, T]]
[[Category: Newman JA]]
[[Category: Newman, J A]]
[[Category: Nunez-Alonso G]]
[[Category: Nunez-Alonso, G]]
[[Category: Picaud S]]
[[Category: Picaud, S]]
[[Category: Tallant C]]
[[Category: Structural genomic]]
[[Category: Vieira LCC]]
[[Category: Tallant, C]]
[[Category: Von Delft F]]
[[Category: Vieira, L C.C]]
[[Category: Chromatin regulator]]
[[Category: Lysine-acetylated histone binding]]
[[Category: Sgc]]
[[Category: Transcription]]

Latest revision as of 13:51, 30 August 2023

Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe

5ign, resolution 1.70Å

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