7c8z: Difference between revisions
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New page: '''Unreleased structure''' The entry 7c8z is ON HOLD Authors: Li, D.F., Hou, Y.J. Description: Crystal structure of salicylate 5-hydroxylase NagGH (a Rieske non-heme iron-dependent mon... |
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==Crystal structure of salicylate 5-hydroxylase NagGH (a Rieske non-heme iron-dependent monooxgenase)== | |||
<StructureSection load='7c8z' size='340' side='right'caption='[[7c8z]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7c8z]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Ralstonia_sp. Ralstonia sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C8Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c8z OCA], [https://pdbe.org/7c8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c8z RCSB], [https://www.ebi.ac.uk/pdbsum/7c8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c8z ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NAGG_RALSP NAGG_RALSP] Oxygenase component of the salicylate 5-hydroxylase (S5H) multicomponent enzyme system which catalyzes the 5-hydroxylation of salicylate to gentisate. Active only on substrates with a ring-substituted carboxylate group with an adjacent hydroxyl group. Primarily active against salicylate and substituted salicylates, but not against 2-hydroxycinnamate, 3-hydroxycinnamate, 2-hydroxyphenylacetate, 3-hydroxyphenylacetate, 2-hydroxybenzophenone, 1-hydroxy-2-naphthoate, 4-methoxysalicylate or 2-hydroxyacetophenone.<ref>PMID:11872705</ref> <ref>PMID:9573207</ref> | |||
==See Also== | |||
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Hou | __TOC__ | ||
[[Category: Li | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Ralstonia sp]] | |||
[[Category: Hou YJ]] | |||
[[Category: Li DF]] | |||