5jef: Difference between revisions

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<StructureSection load='5jef' size='340' side='right'caption='[[5jef]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
<StructureSection load='5jef' size='340' side='right'caption='[[5jef]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jef]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JEF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JEF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jef]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JEF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iji|5iji]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFA:EICOSANE'>LFA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jef OCA], [https://pdbe.org/5jef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jef RCSB], [https://www.ebi.ac.uk/pdbsum/5jef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jef ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jef OCA], [http://pdbe.org/5jef PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jef RCSB], [http://www.ebi.ac.uk/pdbsum/5jef PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jef ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NARQ_ECOLI NARQ_ECOLI]] Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the NarL/NarP proteins. NarQ probably activates NarL and NarP by phosphorylation. NarQ probably negatively regulates the NarL protein by dephosphorylation.  
[https://www.uniprot.org/uniprot/NARQ_ECOLI NARQ_ECOLI] Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the NarL/NarP proteins. NarQ probably activates NarL and NarP by phosphorylation. NarQ probably negatively regulates the NarL protein by dephosphorylation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Histidine kinase]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gordeliy, V]]
[[Category: Gordeliy V]]
[[Category: Gushchin, I]]
[[Category: Gushchin I]]
[[Category: Ishchenko, A]]
[[Category: Ishchenko A]]
[[Category: Melnikov, I]]
[[Category: Melnikov I]]
[[Category: Polovinkin, V]]
[[Category: Polovinkin V]]
[[Category: Popov, A]]
[[Category: Popov A]]
[[Category: Membrane protein]]
[[Category: Nitrate]]
[[Category: Sensor]]
[[Category: Transferase]]

Latest revision as of 11:00, 6 September 2023

Fragment of nitrate/nitrite sensor histidine kinase NarQ (WT) in asymmetric holo state

5jef, resolution 2.42Å

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