2rq9: Difference between revisions

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==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new==
==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new==
<StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [http://pdbe.org/2rq9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [http://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [https://pdbe.org/2rq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Enomoto, M]]
[[Category: Enomoto M]]
[[Category: Hosoda, K]]
[[Category: Hosoda K]]
[[Category: Inoue, Y]]
[[Category: Inoue Y]]
[[Category: Ishii, T]]
[[Category: Ishii T]]
[[Category: Nameki, N]]
[[Category: Nameki N]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Wakamatsu, K]]
[[Category: Wakamatsu K]]
[[Category: Xiang, L]]
[[Category: Xiang L]]
[[Category: Acetylation]]
[[Category: Alternative splicing]]
[[Category: Angiogenesis]]
[[Category: Beta-trefoil]]
[[Category: Developmental protein]]
[[Category: Differentiation]]
[[Category: Growth factor]]
[[Category: Heparin-binding]]
[[Category: Mitogen]]
[[Category: Polymorphism]]
[[Category: Protein binding]]