2w9v: Difference between revisions
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==Solution structure of jerdostatin from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted== | ==Solution structure of jerdostatin from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted== | ||
<StructureSection load='2w9v' size='340' side='right'caption='[[2w9v | <StructureSection load='2w9v' size='340' side='right'caption='[[2w9v]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w9v]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9V OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2w9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_jerdonii Protobothrops jerdonii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9V FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 44 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9v OCA], [https://pdbe.org/2w9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9v RCSB], [https://www.ebi.ac.uk/pdbsum/2w9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DIS_PROJR DIS_PROJR] Recombinant protein inhibits the adhesion of alpha-1/beta-1-K562 (ITGA1/ITGB1) cells to collagen IV with an IC(50) of 80 nM.<ref>PMID:16215260</ref> <ref>PMID:21656569</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9v_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9v_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Calvete | [[Category: Protobothrops jerdonii]] | ||
[[Category: Carbajo | [[Category: Calvete JJ]] | ||
[[Category: Mosulen | [[Category: Carbajo RJ]] | ||
[[Category: Pineda-Lucena | [[Category: Mosulen S]] | ||
[[Category: Sanz | [[Category: Pineda-Lucena A]] | ||
[[Category: Sanz L]] | |||
Latest revision as of 08:01, 23 October 2024
Solution structure of jerdostatin from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted
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