2wc2: Difference between revisions

<table><tr><td colspan='2'>[[2wc2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WC2 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc2 OCA], [http://pdbe.org/2wc2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wc2 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc2 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CRP_ECO57 CRP_ECO57]] A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity).