2yby: Difference between revisions

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<StructureSection load='2yby' size='340' side='right'caption='[[2yby]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
<StructureSection load='2yby' size='340' side='right'caption='[[2yby]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yby]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YBY FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yby]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YBY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yby OCA], [http://pdbe.org/2yby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yby RCSB], [http://www.ebi.ac.uk/pdbsum/2yby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yby ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yby OCA], [https://pdbe.org/2yby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yby RCSB], [https://www.ebi.ac.uk/pdbsum/2yby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yby ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CFAH_MOUSE CFAH_MOUSE]] Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.  
[https://www.uniprot.org/uniprot/CFAH_MOUSE CFAH_MOUSE] Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Caesar, J J.E]]
[[Category: Caesar JJE]]
[[Category: Everett, R J]]
[[Category: Everett RJ]]
[[Category: Johnson, S J]]
[[Category: Johnson SJ]]
[[Category: Lea, S M]]
[[Category: Lea SM]]
[[Category: Tang, C M]]
[[Category: Tang CM]]
[[Category: Complement regulation]]
[[Category: Immune system]]
[[Category: Infection]]
[[Category: Innate immunity]]
Retrieved from "https://proteopedia.org/2yby"